Guardians vs. Phillies Odds & Betting Predictions - May 22, 2026

Guardians at Phillies

10:40 pm • NBCS-PH
1 - 0
Starting Pitchers
pitcherteameraw-l
Cristopher Sanchez logoC.SanchezPhiladelphia Phillies logo1.625-2
Gavin Williams logoG.WilliamsCleveland Guardians logo3.257-3

Guardians at Phillies Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
31-23
+1.5
+1.5-156
o6.5-114
+154
Phillies
26-26
u7.5
-1.5+130
u6.5-103
-185
location pinFriday 10:40 p.m.
May 22, 2026
Citizens Bank ParkPhiladelphia
Guardians vs. Phillies Expert Picks
John Feltman
John Feltman
Last 30d: 5-5-0 (-0.9u)
Under 3.5 (F5)-110
0.5u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 81-103-10 (+6.1u)
Under 7-110
0.91u
@Zerillo ⭐️⭐️⭐️ https://myaction.app/mcSZfWMQl3b
PHI -178
1u
@Zerillo ⭐️⭐️⭐️ https://myaction.app/mcSZfWMQl3b
Austin Pendergrass
Austin Pendergrass
Last 30d: 34-23-0 (+2.2u)
Under 7.5-160
0.31u
Frank Ammirante
Frank Ammirante
Last 30d: 237-262-10 (-13.8u)
Under 7.5-155
1u
Adam Kaufman
Adam Kaufman
Last 30d: 37-46-0 (-14.3u)
CLE +158
1.58u
Sean Zerillo
Sean Zerillo
Last 30d: 176-147-12 (+5.0u)
Under 7-110
0.5u
Bet to 6.5 (-110)
PHI -175
0.88u
Bet to -200

Guardians vs. Phillies Previews & Analysis

  • Adam Trigger's Triple-A Baseball Picks for Friday article feature image

    Adam Trigger's Triple-A Baseball Picks for Friday

    Adam Trigger
    May 22, 2026 UTC
  • Guardians vs Phillies: Feltman's F5 Pick for Friday article feature image

    Guardians vs Phillies: Feltman's F5 Pick for Friday

    John Feltman
    May 22, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Guardians vs. Phillies Public Betting Percentages

Away Logo

Guardians

Public

24%

Bets%

76%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Phillies
16-368-218-1512-264-10
Guardians
30-2416-914-1516-1414-10

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Phillies
24-26-215-13-19-13-120-17-14-9-1
Guardians
26-2812-1314-1515-1511-13

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Phillies
26-2614-1512-1121-175-9
Guardians
31-2315-1016-1318-1213-11

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 20thCINL 4-9-1.5 LO 9.5CIN -154
May 19thCINL 1-4-1.5 LU 8.5CIN -141
May 18thCINW 5-4-1.5 LU 10PHI -125
May 17th@PITW 6-0-5.5 WU 7PHI +110
May 16th@PITW 6-0-1.5 WU 8.5PHI -182

Guardians vs. Phillies Injury Updates

Guardians Injuries

    Phillies Injuries

    • Max Lazar
      RP

      Lazar is out with oblique

      Out

    • Andrew Painter
      SP

      Andrew Painter was seen walking out to bullpen, he won't start but could be available in relief.

      Questionable

    • Steward Berroa
      RF

      Berroa is out with shoulder

      Out

    Guardians vs. Phillies Box Score
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Gavin Williams logoRG.Williams, P998110
    Cade Smith logoRC.Smith, P8110
    HITTERSH-ABRHRRBI
    Angel Martinez logo1A.Martinez, RF0-4000
    Jose Ramirez logo2J.Ramirez, 3B1-4000
    Rhys Hoskins logo3R.Hoskins, 1B0-2000
    Kyle Manzardo logo3K.Manzardo, PH1-1111
    Kyle Manzardo logo3K.Manzardo, 1B1-1111
    David Fry logo4D.Fry, DH2-3000
    Chase DeLauter logo4C.DeLauter, PH0-1000
    Chase DeLauter logo4C.DeLauter, DH0-1000
    Travis Bazzana logo5T.Bazzana, 2B0-4000
    Brayan Rocchio logo6B.Rocchio, SS1-3000
    Steven Kwan logo7S.Kwan, LF0-3000
    Austin Hedges logo8A.Hedges, C1-2000
    Petey Halpin logo9P.Halpin, CF0-3000
    Phillies Player Stats
    Projected
    PITCHERPCIPKER
    Cristopher Sanchez logoLC.Sanchez, P96860
    Jhoan Duran logoRJ.Duran, P14111
    HITTERSH-ABRHRRBI
    Trea Turner logo1T.Turner, SS0-4000
    Kyle Schwarber logo2K.Schwarber, DH0-4000
    Bryce Harper logo3B.Harper, 1B1-4000
    Alec Bohm logo4A.Bohm, 3B0-3000
    Brandon Marsh logo5B.Marsh, LF1-3000
    Adolis Garcia logo6A.Garcia, RF0-3000
    Bryson Stott logo7B.Stott, 2B1-3000
    J.T. Realmuto logo8J.Realmuto, C1-3000
    Justin Crawford logo9J.Crawford, CF0-3000

    Guardians vs. Phillies Odds Comparison

    Right Arrow

    Could not load odds

    Guardians at Phillies Team Totals

    MatchupOverUnder
    Guardians
    31-23
    N/A
    N/A
    Phillies
    26-26
    N/A
    N/A