Indiana vs. Ohio State Odds & Betting Predictions - December 7, 2025
Indiana at Ohio State
1:00 am • FOXIndiana at Ohio State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Indiana 12-0 | +5.5 | +3.5-112 | o45.5-110 | +150 |
 Ohio State 12-0 | u48.5 | -3.5-108 | u45.5-110 | -185 |
Lucas Oil StadiumIndianapolis
Indiana vs. Ohio State Expert Picks
Duck
Last 30d: 216-167-4 (+22.8u)
OSU -125 (Live)
1.25u
Boomer Betz
Last 30d: 139-156-6 (-18.5u)
IU +7.5 (Live)-125
2u
Jeremiah Rose
Last 30d: 40-38-1 (-0.6u)
OSU -170 (Live)
0.25u
Sir Lockselot
Last 30d: 27-76-0 (-58.3u)
OSU -3.5-112
2u
📚Player Profit
Brandon Kravitz
Last 30d: 70-78-3 (+3.4u)
IU +155
0.78u
IU +4+100
1u
Adding to original position
YBK Picks.com
Last 30d: 38-33-1 (+5.3u)
IU +4.5-105
2.86u
Lock & Cash
Last 30d: 14-13-2 (+0.3u)
OSU -4-110
2u
Picks Office
Last 30d: 221-165-4 (+36.7u)
Under 47.5-110
0.91u
Join Discord: https://discord.gg/NcyhmJVXPe
Mjaybrod
Last 30d: 120-111-2 (+8.8u)
OSU u26.5-105
0.95u
Another
Stuck 🚨
Last 30d: 51-61-2 (-5.6u)
IU +4.5-115
0.3u
Pretty close to market. Smaller gut. https://www.actionnetwork.com/ncaaf/college-football-picks-expert-conference-championship-best-bets-ohio-state-vs-indiana-alabama-vs-georgia
Mike Calabrese
Last 30d: 38-51-0 (-0.3u)
IU +142 (1H)
1u
Vegas Refund
Last 30d: 37-40-1 (-6.8u)
IU +4.5-110
1u
Mjaybrod
Last 30d: 120-111-2 (+8.8u)
OSU u26.5-110
0.91u
Sorry Biev
Mike Calabrese
Last 30d: 38-51-0 (-0.3u)
IU +165
1.65u
The Degenerates
Last 30d: 100-91-5 (+1.8u)
OSU -4-110
1.1u
Sean Zerillo
Last 30d: 79-70-1 (+4.5u)
IU +4.5-110
0.25u
Roger Goodell
Last 30d: 44-55-1 (-7.1u)
OSU -3.5-112
1u
THROWING ANOTHER UNIT DOWN. -3.5 ON DK I CAN’T RESIST
Invisible Insider
Last 30d: 10-10-0 (-1.0u)
OSU -4-110
0.75u
Am I falling for it? They’re so much better.
The Propfessor
Last 30d: 55-55-0 (-3.2u)
J.Smith o5.5 Recs-125
0.8u
Jeremiah looks to step up in the big stage once again, this time, in his first Big 10 Championship.
Smith this season has gone over this number in 7/11 games overall, averaging 6.5 per game. When he runs 20+ routes, he is over in 7/9 games, averaging 8.8 targets per game.
He will now faces Indiana in the battle between the undefeateds, and #1 and #2 in the nation.
Opposing WRs have been able to find success against this defense most of the season. Smith will be finding his spots all game long and I love this spot for him to rack up the grabs.
Indiana’s run defense is very elite, ranking top 5 in the nation in success rate, stuff rate, and line yards on the season. Expecting the OSU offense to lean on Julian Sayin and the passing game a lot more than usual in this one.
Indiana also runs a ton of zone coverage. Jeremiah feasts against zone and is OSU’s best WR by far against it, with a 0.32 TPRR against zone coverage on the year.
Last season, in the postseason, we saw Smith have 7+ targets in 3/4 games. Love for this to continue for him tomorrow…
Cam Is Money
Last 30d: 138-122-3 (+5.6u)
IU +4-110
0.91u
Brandon Kravitz
Last 30d: 70-78-3 (+3.4u)
IU +4+100
1u
Big Bets On Campus (CFB)
Last 30d: 60-70-1 (-10.0u)
IU +6-110
0.91u
@Stuckey2 @_Collin1 https://myaction.app/SXl6WrC0QYb
Dan Gaspar
Last 30d: 55-46-4 (+3.0u)
K.Black o32.5 Rush Yds-115
1u
B.Inniss o14.5 Rec Yds-115
1.15u
R.Hemby o3.5 Rec Yds-115
1u
Sandy Plashkes
Last 30d: 118-141-6 (-29.3u)
IU +4-110
2u
Picks Office
Last 30d: 221-165-4 (+36.7u)
IU +4.5-110
0.91u
Join Discord: https://discord.gg/NcyhmJVXPe
Roger Goodell
Last 30d: 44-55-1 (-7.1u)
OSU -4-110
1u
💰🦡 Jake
Last 30d: 98-114-2 (-7.0u)
IU +145 (1H)
0.75u
Dan Gaspar
Last 30d: 55-46-4 (+3.0u)
F.Mendoza u22.5 Rush Yds-115
1u
Duck
Last 30d: 216-167-4 (+22.8u)
Under 24.5 (1H)-132
1u
Moneyline Hacks
Last 30d: 161-140-3 (+50.1u)
IU +4.5-106
0.94u
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Collin Wilson
Last 30d: 91-76-1 (+5.5u)
IU +6-110
1u
Project Ohio State -4
Indiana vs. Ohio State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Indiana vs. Ohio State Public Betting Percentages
Betting Trends
- Ohio State are 5-0 in their last 5 games.
- Ohio State are 4-1 in their last 5 games against the spread
- Ohio State are 4-1 in their road games against the spread
- The totals have gone OVER in 2 of Ohio State' last 5 games
- The totals have gone OVER in 4 of Ohio State' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 10-2 | 6-1 | 4-1 | 9-2 | N/A |
| 7-5 | 4-3 | 3-2 | 5-5 | 1-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-8 | 4-3 | 0-5 | 3-8 | N/A |
| 8-4 | 5-2 | 3-2 | 7-3 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 12-0 | N/A | N/A | 11-0 | N/A |
| 12-0 | N/A | N/A | 10-0 | 1-0 |
Last 5 Matchups
Team Stats
222
YDS
264
15/23
Comps/Atts
22/30
9.652173913043478
YPA
8.8
1/1
TDs/INTs
1/1
3/10
Sacks/Yards
5/29
5/49
Penalties/Yards
2/20
Indiana vs. Ohio State Odds Comparison
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Indiana at Ohio State Team Totals
MatchupOverUnder | ||
|---|---|---|
Indiana 12-0 | N/A | N/A |
Ohio State 12-0 | N/A | N/A |