IND @ BUF
6:00 pm • CBSColts vs. Bills Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Colts 9-7 | +7 | +7-114 | o49.5-107 | +242 |
![]() Bills 11-6 | u50 | -7-102 | u49.5-111 | -299 |

Colts vs. Bills Game Analysis
Colts vs. Bills Preview: Indy Run Game Will Keep Things Close
Raybon's Matchups Breakdown & Picks For Week 11
How We're Betting Sunday's Main NFL Slate
3 Ways We're Betting Sunday's Early NFL Games
NFL Survivor Pool Picks & Strategy For Week 11 (& Beyond)
Koerner's Week 11 Pick'Em Confidence Rankings
Koerner's Final Fantasy Tiers For Week 11
Anderson's 'Bet or Wait' For Every Week 11 NFL Game
Our Fantasy Football Trade Deadline Cheat Sheet
Koerner's Top 5 PrizePicks Plays For Week 11
Previte: 12 Fantasy Trade Deadline Candidates To 'Buy, Sell, Hold'
Anderson: Why I Already Bet the Colts To Cover Against the Bills
Best NFL Betting Sites
Colts vs. Bills Expert Picks
Popular Props
Rec Yds
10 propsRush Yds
4 propsRecs
7 propsAnytime Touchdown Scorer
32 propsFirst Touchdown Scorer
32 propsPass Yds
2 propsPass TDs
2 propsPass Comp
1 propLongest Completion
1 propLongest Reception
7 propsLongest Rush
4 propsRush Att
1 propPass Att
2 propsLast 5 Matchups
Betting Trends
- Bills are 1-1 in their last 5 games.
- Bills are 1-1 in their last 5 games against the spread
- Bills are 0-1 in their road games against the spread
- The totals have gone OVER in 2 of Bills' last 2 games
- The totals have gone OVER in 1 of Bills' 1 last games at home
Colts vs. Bills Public Betting
Matchup History
Against the Spread (ATS) History
Over/Under History
Bills vs. Colts Injury Updates
Bills Injuries
Jordan Phillips
DTJordan Phillips (Knee) is questionable this week.
Questionable
Bobby Hart
TBobby Hart (Inactive) is out this week.
Out
Shaq Lawson
DEShaq Lawson (wrist) is questionable this week.
Questionable
Eli Ankou
DTEli Ankou (Inactive) is out this week.
Out
Tre'Davious White
CBTre'Davious White (Knee) is out for the season.
Out for Season
Tommy Sweeney
TETommy Sweeney (Inactive) is out this week.
Out
Joe Giles-Harris
LBJoe Giles-Harris (Inactive) is out this week.
Out
Marquez Stevenson
WRMarquez Stevenson (Inactive) is out this week.
Out
Colts Injuries
Brandon King
LBBrandon King (Toe) is questionable this week.
Questionable
Stephon Gilmore
CBStephon Gilmore (Groin) is out this week.
Out
Ryan Kelly
CRyan Kelly (Neck) is out this week.
Out
DeForest Buckner
DTDeForest Buckner (Knee) is questionable this week.
Questionable
Tony Brown
CBTony Brown (Inactive) is out this week.
Out
Khari Willis
SAFKhari Willis (ankle) is questionable this week.
Questionable
Julian Blackmon
SAFJulian Blackmon (achilles) is out this week.
Out
Chris Williams
DTChristopher Williams (Undisclosed) is out this week.
Out
Chris Wilcox
CBChris Wilcox (COVID Protocols) is out this week.
Out
Mike Strachan
WRMike Strachan (Undisclosed) is out this week.
Out
Player Stats
passing yards
--pydspassing touchdowns
--ptdrushing yards
--rydsrushing touchdowns
--rtd
Team Stats
Line Move Data
Time | IND line | BUF line |
---|---|---|
11/21/2021, 5:53 PM | +7 -114 | -7 -102 |
11/21/2021, 5:49 PM | +7 -110 | -7 -106 |
11/21/2021, 5:38 PM | +7 -114 | -7 -102 |
11/21/2021, 5:37 PM | +7 -110 | -7 -106 |
11/21/2021, 5:20 PM | +7 -114 | -7 -102 |
11/21/2021, 5:17 PM | +7 -110 | -7 -106 |
11/21/2021, 5:14 PM | +7 -114 | -7 -102 |
11/21/2021, 5:13 PM | +7 -111 | -7 -106 |
11/21/2021, 5:12 PM | +7 -107 | -7 -107 |
11/21/2021, 5:11 PM | +7 -108 | -7 -107 |
Compare Odds
SportsBook | IND | BUF |
---|---|---|
Consensus | +7-114 | -7-102 |
Open | +7-110 | -7-110 |
Best Line |
Colts vs. Bills Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Colts 9-7 | o20.5-110 | u20.5-120 |
![]() Bills 11-6 | o28.5-110 | u28.5-120 |