Promotion Banner

IND @ BUF

6:00 pm • CBS

Indianapolis Colts

4-12-1
41
41 - 15

Buffalo Bills

13-3
15

Colts vs. Bills Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Colts
4-12-1
+7
+7-114
o49.5-107
+242
Bills
13-3
u50
-7-102
u49.5-111
-299
location pinSunday 6:00 p.m.
November 21, 2021
Highmark StadiumBuffalo

Colts vs. Bills Game Analysis

  • Raybon's Matchups Breakdown & Picks For Week 11

    Chris Raybon•
    Nov 21, 2021 UTC

  • How We're Betting Sunday's Main NFL Slate

    Action Network Staff•
    Nov 21, 2021 UTC

  • 3 Ways We're Betting Sunday's Early NFL Games

    Action Network Staff•
    Nov 21, 2021 UTC

  • NFL Survivor Pool Picks & Strategy For Week 11 (& Beyond)

    Travis Reed•
    Nov 21, 2021 UTC
See more NFL Coverage Right Arrow

Offers

Right Arrow
No promotions available. Try selecting a different location.

Colts vs. Bills Expert Picks

IND
BUF
IND Spread
5
BUF Spread
2
Over
0
Under
3
IND ML
1
BUF ML
0
Vegas Refund
Stuck 🚨
+7

Casinos

Right Arrow
No promotions available. Try selecting a different location.

Popular Props

No props found

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 14th@NYJW 45-17-13.5 WO 48.5BUF -820
Nov 7th@JACL 6-9-16 LU 48.5JAC -1161
Oct 31stMIAW 26-11-14.5 WU 48.5BUF -1024
Oct 19th@TENL 31-34-6 LO 53.5TEN -262
Oct 11th@KCW 38-20+3 WO 56.5BUF +122

Betting Trends

  • Bills are 1-1 in their last 5 games.
  • Bills are 0-2 in their last 5 games against the spread
  • The totals have gone OVER in 1 of Bills' last 2 games
  • The totals have gone OVER in 1 of Bills' 2 last games at home

Colts vs. Bills Public Betting

Colts

Public

Home Logo

Bills

57%

Bets%

43%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Bills		0-20-2N/A0-2N/A
Colts		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Bills		1-11-1N/A1-1N/A
Colts		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Bills		13-31-1N/A1-1N/A
Colts		4-12-1N/AN/AN/AN/A

Bills vs. Colts Injury Updates

Bills Injuries

  • Jordan Phillips

    DT

    Phillips is questionable with shoulder

    Questionable

  • DaQuan Jones

    DT

    Jones is questionable with calf

    Questionable

  • Micah Hyde

    S

    Hyde is out for season with neck

    Out for Season

  • Brandon Shell

    OL

    Shell is questionable with knee

    Questionable

  • Ike Boettger

    G

    Ike Boettger (Achilles) is out this week.

    Out

  • Deonte Harty

    WR

    Harty is out with foot

    Out

  • David Edwards

    G

    Edwards is out with concussion

    Out

  • Tommy Doyle

    T

    Doyle is out with knee

    Out

Colts Injuries

  • Rigoberto Sanchez

    P

    Sanchez is out for season with achilles

    Out for Season

  • Kenny Moore II

    CB

    Moore II is out with ankle

    Out

  • Shaquille Leonard

    LB

    Leonard is out with back

    Out

  • Ashton Dulin

    WR

    Dulin is questionable with concussion

    Questionable

  • Kaden Smith

    TE

    Kaden Smith (Knee) is out this week.

    Out

  • Jonathan Taylor

    RB

    Taylor is out for season with ankle

    Out for Season

  • Carter O'Donnell

    T

    Carter O'Donnell (Undisclosed) is out this week.

    Out

  • Kylen Granson

    TE

    Granson is out with ankle

    Out

  • Andrew Ogletree

    TE

    Andrew Ogletree (Knee) is out for the season.

    Out for Season

See more NFL Injuries Right Arrow

Team Stats

Total

370
Total Yards
307
66
Total Plays
54
5.6
Yards Per Play
5.7

Passing

106
YDS
228
11/20
Comps/Atts
24/40
5.3
YPA
5.268
1/0
TDs/INTs
2/3
0/0
Sacks/Yards
1/12

Rushing

264
Rush Yards
91
46
Attempts
13
5.739
YPC
7
4
TDs
0

Turnovers

0
Fumbles Lost
1
0
Interceptions
3

Efficiency

4/6 66.67%
Redzone
2/2 100%
8/12 0%
3rd Down
5/10 0%
0/1 0%
4th Down
0/0 0%

First Downs

28
Total
19
6
Pass
13
18
Rush
5
4
Penalty
1

Misc

3/30
Penalties/Yards
7/56
37:56
Possession
22:04

Compare Odds

Right Arrow

Could not load odds

See more NFL Odds Right Arrow

Colts vs. Bills Team Totals

MatchupOverUnder
Colts
4-12-1
o20.5-110
u20.5-120
Bills
13-3
o28.5-110
u28.5-120

Offers

Right Arrow
No promotions available. Try selecting a different location.