Week 6 NFL Betting Market: 49ers-Rams Boasts Unique Spread & Over/Under Activity

Key Numbers

Eagles at Vikings (-3): The Vikings bounced back in a big way after laying a complete egg vs. the Bears. Kirk Cousins shocked the world and threw for more than 300 yards, albeit against the Giants. Shocking that throwing the ball to some high-quality receivers would lead to points being scored.

Despite their showing in New York, the Vikings are still getting the fade treatment on Sunday. Just one-third of bettors are laying three points on the Vikes and a quarter of moneyline bettors are taking them straight-up. Though Philly is getting all that love, the line has remained on the key number of three. It's likely going to take some sharp action on the Eagles to get that line to budge.

49ers at Rams (-3): Don't look now, but if Jimmy G and the Niners can topple LA, the Rams are going to be in trouble. Last year's Super Bowl loser has lost two straight and will still be in third place in the NFC West even if they win this game.

Odds as of Wednesday at 2:30 p.m. ET. Check out via PointsBet, where Action Network users get an exclusive 200% deposit match (deposit $50, bet with $150).

Unlike the Eagles-Vikings game, bets are right around 50/50 for this spread. Also unlike the previously mentioned affair, this line has moved from SF +3.5/+4 down to the key number of +3 thanks to sharp action.

We've tracked two Bet Signals on the Niners, as some sharps are clearly buying into their undefeated record. Now that the line is on the key number, it will be interesting to see whether any more sharp action comes in on either side.

Popular Sides

49ers-Rams Over (87%): Ah, this game again. Considering the previous two Rams games have had 95 and 59 points scored, respectively, it's not all too surprising to see this over being hammered.

The onslaught of action has caused the line to jump up two points, from 48.5 to 50.5.

Seahawks (82%) at Browns: One week the Browns look excellent, the next week they look like garbage. That's just how this season has gone for Cleveland, which is actually in line to be good this week after the terrible performance vs. the 49ers. That is assuming, of course, that you believe the zig-zagging continues.

The lookahead line had the Browns at -2.5, but the spread reopened at SEA -1 on Tuesday morning. Since then, the Seahawks have moved into the -1.5/-2 range, but will likely need a big wave of sharp action to hit -3 on the road.

Falcons (80%) at Cardinals: I'm kind of shocked to see the Falcons, who are 1-4 against the spread this year, commanding a casual 80% of bets on the road. After the line was readjusted to ATL -2.5 on Sunday night, this line hasn't really moved whatsoever. The Cards have seen some sharp action on their side, which has helped keep this line from going to ATL -3 or higher.

Biggest Movers

Giants-Patriots Total: Wild, wild weather in New England! The wet and windy storm, in addition to the Giants having no players available on offense, have caused this over/under to fall from 46 to 41 … that's five whole points for those who have math difficulties. Over/under bets are split, but the under is getting 75% of the loot.

Panthers-Bucs: A London game that's actually in the morning, what a grand idea … although I guess some people don't like the morning games. Probably West Coast folk.

After opening as a 1-point neutral dog, the Panthers are now -2. Most of the movement took place within 24 hours of the line opening. Since then, money has been flowing in on Tampa. Don't be surprised if this sucker heads back towards a pick 'em.