Week 16 NFL Betting Odds: Spreads & Over/Unders for Every Game

Week 16 NFL Betting Odds: Spreads & Over/Unders for Every Game article feature image
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USA Today Sports. Pictured: Carson Wentz, Dak Prescott

  • Looking for Week 16 NFL odds? We've got you covered.
  • You'll find spreads and over/unders for every game outlined below.
  • On the docket: The Cowboys (-2.5) at Eagles, Packers at Vikings (-4) and more.

The 2019 Miami Dolphins are finally favored. By one point. At home. Against the 1-13 Cincinnati Bengals. But still a notable development nonetheless.

We have a full weekend of NFL action ahead, with a trio of Saturday games: Texans-Buccaneers, Bills-Patriots and Rams-49ers.

Below you'll find odds for every game Week 16 game, featuring spreads and over/unders.


Odds as of Monday morning and via DraftKings, where Action Network users get a risk-free bet up to $500.


Week 16 NFL Odds

Houston Texans at Tampa Bay Buccaneers

  • Odds: Texans -2
  • Over/Under: 53
  • Time: 1 p.m. ET on Saturday
  • TV Channel: NFL Network

Buffalo Bills at New England Patriots

  • Odds: Patriots -6
  • Over/Under: 38.5
  • Time: 4:30 p.m. ET on Saturday
  • TV Channel: NFL Network

Los Angeles Rams at San Francisco 49ers

  • Odds: 49ers -6.5
  • Over/Under: 46
  • Time: 8:15 p.m. ET on Saturday
  • TV Channel: NFL Network

Jacksonville Jaguars at Atlanta Falcons

  • Odds: Falcons -7.5
  • Over/Under: 45.5
  • Time: 1 p.m. ET on Sunday
  • TV Channel: FOX

Baltimore Ravens at Cleveland Browns

  • Odds: Ravens -9.5
  • Over/Under: 49
  • Time: 1 p.m. ET on Sunday
  • TV Channel: CBS

New Orleans Saints at Tennessee Titans

  • Odds: Saints -1.5
  • Over/Under: 51
  • Time: 1 p.m. ET on Sunday
  • TV Channel: FOX

Carolina Panthers at Indianapolis Colts

  • Odds: Colts -6.5
  • Over/Under: 46.5
  • Time: 1 p.m. ET on Sunday
  • TV Channel: FOX

Cincinnati Bengals at Miami Dolphins

  • Odds: Dolphins -1
  • Over/Under: 46
  • Time: 1 p.m. ET on Sunday
  • TV Channel: CBS
2020-nfl draft order-projections-dolphins-first-overall-pick-redskins
Steve Mitchell-USA TODAY Sports. Pictured: Ryan Fitzpatrick, DeVante Parker

Pittsburgh Steelers at New York Jets

  • Odds: Steelers -3
  • Over/Under: 39
  • Time: 1 p.m. ET on Sunday
  • TV Channel: CBS

New York Giants at Washington Redskins

  • Odds: Redskins -2.5
  • Over/Under: 42
  • Time: 1 p.m. ET on Sunday
  • TV Channel: FOX

Detroit Lions at Denver Broncos

  • Odds: Broncos -6.5
  • Over/Under: 37.5
  • Time: 4:05 p.m. ET on Sunday
  • TV Channel: CBS

Oakland Raiders at Los Angeles Chargers

  • Odds: Chargers -5.5
  • Over/Under: 47
  • Time: 4:05 p.m. ET on Sunday
  • TV Channel: CBS

Dallas Cowboys at Philadelphia Eagles

  • Odds: Cowboys -2.5
  • Over/Under: 47.5
  • Time: 4:25 p.m. ET on Sunday
  • TV Channel: FOX

Arizona Cardinals at Seattle Seahawks

  • Odds: Seahawks -9.5
  • Over/Under: 51
  • Time: 4:25 p.m. ET on Sunday
  • TV Channel: FOX

Kansas City Chiefs at Chicago Bears

  • Odds: Chiefs -5
  • Over/Under: 45
  • Time: 8:20 p.m. ET on Sunday
  • TV Channel: NBC

Green Bay Packers at Minnesota Vikings

  • Odds: Vikings -4
  • Over/Under: 46.5
  • Time: 8:15 p.m. ET on Monday
  • TV Channel: ESPN

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