NFL Odds & Picks for Buffalo Bills vs. Denver Broncos: Big Bets Moving Saturday’s Spread

NFL Odds & Picks for Buffalo Bills vs. Denver Broncos: Big Bets Moving Saturday’s Spread article feature image
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Photo by Ralph Freso/Getty Images. Pictured: Safety Micah Hyde #23 of the Buffalo Bills celebrates with teammate Jordan Poyer #21

  • The Buffalo Bills take on the Denver Broncos in Saturday NFL Week 15 action.
  • The Bills are currently 5.5-point favorites over the Broncos, but the spread has not always been at that number.
  • See the latest Bills vs. Broncos odds, including how sharps are betting Saturday afternoon's spread.

NFL Odds: Bills vs. Broncos

Bills Odds -5.5
Broncos Odds +5.5
Over/Under 49
PRO Projections Bills -4.9 | O/U: 49
Time/Channel  4:30 p.m. ET, NFL Network
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Along with other great crossovers throughout history, like Family Guy/The Simpsons, Boy Meets World/Sabrina The Teenage Witch and That’s So Raven/The Suite Life Of Zack & Cody/Hannah Montana, comes another epic crossover event on Saturday.

College football conference championships and NFL action.

Getting us started on the professional side will be Bills vs. Broncos at 4:30 p.m. ET, and according to our PRO betting tools, big bettors are just as excited about this matchup — and its line value — as the average fan.

Money has Bills vs. Broncos odds on the move, so let’s look at the bet attracting the big bucks …

NFL Picks: Bills vs. Broncos

Buffalo opened as a 5-point favorite and has stretched to a consensus of -5.5 (click here for the latest NFL odds), with some books even touching -6.

While we haven’t tracked any specific instances of sharp money steaming the market, a steady pounding of big bets is responsible for this line movement.

Public bettors believe in the Bills, as 64% of spread tickets are backing Buffalo.

In addition, 82% of the money is on the road favorites as well, telling us which side is landing the biggest wagers as well.

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Our NFL model’s biggest weekly edges

Profitable data-driven system picks

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