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NFL Odds & Picks For Packers vs. 49ers: How To Bet the Thursday Night Football Spread

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Getty Images. Pictured: Kyle Shanahan, Aaron Rodgers

NFL Odds For Packers vs. 49ers

Packers Odds
-7.5 [BET NOW]
49ers Odds
+7.5 [BET NOW]
Over/Under
48.5 [BET NOW]
Kickoff
8:20 p.m. ET
TV
FOX
Odds via PointsBet, where you can win $125 if the Packers gain a yard against the 49ers.

Aaron Rodgers will be looking for revenge in a rematch of the 2019 NFC Championship Game, when the Packers lost to the 49ers, 37-20. But the Packers are in much better shape this time around while the 49ers have been decimated by injury.

If I had to rank the top five 49ers players by how many points they’re worth to the spread, it would be: Jimmy Garoppolo, Nick Bosa, George Kittle, Deebo Samuel and Richard Sherman. All five are either out, on Injured Reserve or on the COVID-19 list.

Garoppolo and Kittle sustained their injuries this past Sunday, so the proximity to Thursday had a significant impact on the spread. The lookahead line had this matchup right around a pick ’em, but that has since moved roughly 7.5 points, which feels aggressive.

I had the Packers power rated as 1-point favorites for this matchup before Week 8, then after Garoppolo and Kittle suffered their injuries, I moved the line to Packers -6 (Jimmy G is worth about three points while Kittle is worth about one to one-and-a-half points). I also added another point to account for the cluster of injuries at wide receiver.

But the 49ers may be able to overcome their absences thanks to Kyle Shanahan — one of the more underrated coaches in the NFL.

I expect Shanahan to have a run-heavy game script on Thursday and to attack a Packers run funnel defense that just gave up 163 yards and three touchdowns to Vikings running back Dalvin Cook. It helps that the 49ers offense is more of a “system” that allows backups like JaMycal Hasty and Jerick McKinnon — their only healthy running backs — to step in and thrive.

The Packers could be in similar shape, as Jamaal Williams and A.J. Dillon are out due to COVID-19 while Aaron Jones is questionable with a calf injury.

If Jones and left tackle David Bakhtiari are both ultimately ruled out, I would lower the Packers from -6 to -5, meaning there could be even more value in this number once inactives are released. In that scenario, I like getting the 49ers +7.5, but as always, props will offer more value — I’ll release my prop pick for this game on Thursday afternoon.

PICK: 49ers +7.5 if Jones and Bakhtiari are ruled out

[Bet now at PointsBet and get $125 if the Packers gain a yard]

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