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MLB Opening Day Odds, Pitching Matchups

MLB Opening Day Odds, Pitching Matchups article feature image

Brad Penner-USA TODAY Sports. Pictured: Masahiro Tanaka.

  • Though the Mariners and Athletics played in Japan last week, the true MLB opening day is Thursday and opening odds are out.
  • Two terrific pitching matchups headline the slate, with Jacob deGrom and the Mets taking on Max Scherzer and the Nationals (1:05 p.m. ET) and Justin Verlander and the Astros visiting Blake Snell and the Rays (4:10 p.m. ET).
  • At -300, Masahiro Tanaka and the Yankees are the 2nd biggest opening day favorites we have on record against the Orioles.

Opening Day odds are here! Last Thursday, we had March Madness action all day. This Thursday, America’s Pastime arrives. Buckle up, it’s going to be a long summer.

There are a few matchups that stick out in particular, with Mets-Nats leading the way at 1:05 p.m. ET. Reigning Cy Young winner Jacob deGrom takes on a 3-time winner of the award and last year’s runner-up, Max Scherzer, in a matchup that kicks off what will be a competitive NL East race.

Unfortunately, the nationally televised game in that time slot is Orioles-Yankees, which currently boasts the second largest favorite in Opening Day history in our database (Kershaw -355 vs. Padres, 2017).

The 4 p.m. showdown between Justin Verlander and Blake Snell is the second Cy Young vs. Cy Young runner-up matchup of the day. Though Snell took home the hardware, it’s the Astros and their potent lineup who have opened as slight road favorites.

The only night game will be in Seattle, where the 2-0 Mariners host Chris Sale and the World Series champion Red Sox. Opening at -172, Boston is easily the largest road favorite of the Thursday slate.

Keep your eyes open for sharp action, model picks, props and more opening day content in the next 48 hours.

Baltimore Orioles at New York Yankees

Andrew Cashner vs. Masahiro Tanaka

1:05 p.m. ET (ESPN)

Orioles +268 / Yankees -300

Over/under: 9 (u-125)

New York Mets at Washington Nationals

Jacob deGrom vs. Max Scherzer

1:05 p.m. ET

Mets +130 / Nationals -140

Over/under: 7 (u-130)

St. Louis Cardinals at Milwaukee Brewers

Miles Mikolas vs. Jhoulys Chacin

2:10 p.m. ET

Cardinals +106 / Brewers -116

Over/under: 8.5

Atlanta Braves at Philadelphia Phillies

Julio Teheran vs. Aaron Nola

3:05 p.m. ET

Braves +170 / Phillies -180

Over/under: 7.5 (o-120)

Detroit Tigers at Toronto Blue Jays

Jordan Zimmermann vs. Marcus Stroman

3:37 p.m. ET

Tigers +150 / Blue Jays -160

Over/under: 8.5 (o-120)

Houston Astros at Tampa Bay Rays

Justin Verlander vs. Blake Snell

4:00 p.m. ET

Astros -110 / Rays +100

Over/under: 6.5 (o-125)

Chicago Cubs at Texas Rangers

Jon Lester vs. Mike Minor

4:05 p.m. ET

Cubs -130 / Rangers +120

Over/under: 9.5

Los Angeles Angels at Oakland Athletics

Trevor Cahill vs. Mike Fiers

4:07 p.m. ET

Angels +120 / Athletics -130

Over/under: 9 (o-130)

Pittsburgh Pirates at Cincinnati Reds

Jameson Taillon vs. Luis Castillo

4:10 p.m. ET

Pirates +100 / Reds -110

Over/under: 8.5 (u-120)

Arizona Diamondbacks at Los Angeles Dodgers

Zack Greinke vs. Hyun-Jin Ryu

4:10 p.m. ET (ESPN)

Diamondbacks +135 / Dodgers -145

Over/under: 7.5

San Francisco Giants at San Diego Padres

Madison Bumgarner vs. Eric Lauer

4:10 p.m. ET

Giants +105 / Padres -115

Over/under: 8 (u-125)

Colorado Rockies at Miami Marlins

Kyle Freeland vs. Jose Urena

4:10 p.m. ET

Rockies -130 / Marlins +120

Over/under: 8 (u-125)

Cleveland Indians at Minnesota Twins

Corey Kluber vs. Jose Berrios

4:10 p.m. ET

Indians -135 / Twins +125

Over/under: 7.5 (o-120)

Chicago White Sox at Kansas City Royals

Carlos Rodon vs. Brad Keller

4:15 p.m. ET

White Sox -105 / Royals -105

Over/under: 8.5 (o-120)

Boston Red Sox at Seattle Mariners

Chris Sale vs. Marco Gonzales

7:10 p.m. ET (ESPN)

Red Sox -172 / Mariners +162

Over/under: 7 (o-130)

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