Illinois vs. Duke Odds & Betting Predictions - September 6, 2025

Illinois at Duke

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Illinois Fighting Illini

@

Duke Blue Devils

MatchupOpenSpreadTotalMoneyline
Illinois 10-3	-1.5	-1.5-106	o49.5-115	-115
Duke 9-4	u49.5	+1.5-114	u49.5-105	-104

location pin

Saturday 4:00 p.m.

September 06, 2025

Brooks Field at Wallace Wade StadiumDurham

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NCAAF Public Betting

Duke are 4-1 in their last 5 games.
Duke are 4-1 in their last 5 games against the spread
Duke are 4-1 in their road games against the spread
The totals have gone OVER in 3 of Duke' last 5 games
The totals have gone OVER in 2 of Duke' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Duke	8-3-1	4-2	4-1-1	3-2	5-1-1
Illinois	8-4	4-3	4-1	3-2	5-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Duke	5-7	2-4	3-3	1-4	4-3
Illinois	5-7	2-5	3-2	3-2	2-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Duke	9-3	N/A	N/A	5-0	4-3
Illinois	9-3	N/A	N/A	5-0	4-3

date	opponent	score	spread	over/under	moneyline
Jan 3rd	@MISS	L 20-52	+18.5 L	O 51.5	MISS +650
Nov 30th	@WF	W 23-17	-3.5 W	U 53.5	DUKE -165
Nov 24th	VT	W 31-28	+2.5 W	O 45.5	DUKE +114
Nov 9th	@NCST	W 29-19	+3.5 W	U 51.5	DUKE +128
Nov 2nd	@MIA	L 31-53	+21 L	O 55.5	MIA +903

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MatchupOverUnder
Illinois 10-3	N/A	N/A
Duke 9-4	N/A	N/A