Purdue vs. Notre Dame Odds & Betting Predictions - September 20, 2025

Purdue at Notre Dame

4:00 pm

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Purdue Boilermakers

@

Notre Dame Fighting Irish

MatchupOpenSpreadTotalMoneyline
Purdue 1-11	N/A	N/A	N/A
Notre Dame 14-2	N/A	N/A	N/A

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Saturday 4:00 p.m.

September 20, 2025

Notre Dame StadiumSouth Bend

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NCAAF Public Betting

Notre Dame are 4-1 in their last 5 games.
Notre Dame are 4-1 in their last 5 games against the spread
Notre Dame are 3-0 in their road games against the spread
The totals have gone OVER in 3 of Notre Dame' last 5 games
The totals have gone OVER in 3 of Notre Dame' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Notre Dame	10-2	4-2	3-0	9-2	1-0
Purdue	3-9	1-5	2-4	0-1	2-8

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Notre Dame	7-5	3-3	2-1	7-4	0-1
Purdue	7-5	3-3	4-2	1-0	6-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Notre Dame	11-1	N/A	N/A	10-1	1-0
Purdue	1-11	N/A	N/A	0-1	0-10

date	opponent	score	spread	over/under	moneyline
Jan 21st	OSU	L 23-34	+8.5 L	O 45.5	OSU +295
Jan 10th	@PSU	W 27-24	+1.5 W	O 45.5	ND -102
Jan 2nd	@UGA	W 23-10	-1.5 W	U 45.5	ND -110
Dec 21st	IU	W 27-17	-7 W	U 50.5	ND -270
Nov 30th	@USC	W 49-35	-7 W	O 52.5	ND -256

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MatchupOverUnder
Purdue 1-11	N/A	N/A
Notre Dame 14-2	N/A	N/A