Reds vs. Cardinals Odds & Betting Predictions - June 21, 2025
Reds at Cardinals
6:15 pm • FDSOHStarting Pitchers
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Reds at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Reds 39-36 | +1.5 | +1.5-125 | o9-115 | +164 |
![]() Cardinals 40-35 | u9 | -1.5+104 | u9-105 | -196 |

Busch StadiumSt. Louis
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Prop Odds Comparison
Line Movement Tracker
Reds vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 4-1 in their last 5 games.
- Cardinals are 4-1 in their last 5 games against the spread
- Cardinals are 21-18 in their road games against the spread
- The totals have gone OVER in 3 of Cardinals' last 5 games
- The totals have gone OVER in 20 of Cardinals' 36 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Cardinals vs. Reds Injury Updates

Cardinals Injuries

Reds Injuries
- Noelvi Marte3B
Marte is day-to-day with side
Day-to-Day
- Brandon WilliamsonSP
Williamson is out for season with elbow
Out for Season
- Graham AshcraftRP
Ashcraft is out with groin
Out
- Julian AguiarSP
Aguiar is out for season with elbow
Out for Season
- Rhett LowderSP
Lowder is out with elbow
Out
- Carson SpiersRP
Spiers is out with shoulder
Out
Reds vs. Cardinals Odds Comparison
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Reds at Cardinals Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Reds 39-36 | N/A | N/A |
![]() Cardinals 40-35 | N/A | N/A |