Pirates vs. Cardinals Odds & Betting Predictions - August 27, 2025

Pirates at Cardinals

11:45 pm • SportsNet PT

Pittsburgh Pirates

58-75

2 - 1

St. Louis Cardinals

65-68

MatchupOpenSpreadTotalMoneyline
Pirates 58-75	+1.5	+1.5-149	o7.5+100	+144
Cardinals 65-68	u7.5	-1.5+125	u7.5-121	-174

Wednesday 11:45 p.m.

August 27, 2025

Busch StadiumSt. Louis

PIT +146

0.68u

STL -1.5+119

📚Player Profit 🔑 St. Louis Cardinals -1.5 +119 (Player Profit) 2u Walking Locks Ep. 2 Cardinals in a perfect bounce back spot at home after getting waxed by the damn Pirates last night. Now they have their ace in Sonny Gray on the mind and he’s been up and down but has the stuff to absolutely dominate a lineup like the Pirates. Cardinals bats will be able to get to PIT pitching who is going with a bullpen game here. Love this spot and value for the Cards

Pirates vs Cardinals: Best Bet for Tonight
Action Network Staff•
Aug 27, 2025 UTC

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No props found

MLB Public Betting

Cardinals are 2-3 in their last 5 games.
Cardinals are 1-4 in their last 5 games against the spread
Cardinals are 33-33 in their road games against the spread
The totals have gone OVER in 4 of Cardinals' last 5 games
The totals have gone OVER in 35 of Cardinals' 67 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	66-67	33-34	33-33	23-36	42-31
Pirates	73-60	42-27	31-33	17-23	54-37

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	68-58-7	35-29-3	33-29-4	30-24-5	37-34-2
Pirates	53-72-8	28-36-5	25-36-3	16-22-2	36-49-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	65-68	36-31	29-37	30-29	34-39
Pirates	58-75	39-30	19-45	20-20	37-54

date	opponent	score	spread	over/under	moneyline
Aug 26th	PIT	L 3-8	-1.5 L	O 8	PIT -126
Aug 25th	PIT	W 7-6	-1.5 L	O 8	STL -132
Aug 24th	@TB	L 2-7	+1.5 L	U 9	TB +125
Aug 22nd	@TB	L 6-10	+1.5 L	O 9	TB +117
Aug 21st	@TB	W 7-4	-1.5 W	O 8.5	STL -119

Nolan Arenado
3B
Arenado is out with shoulder
Out
Brendan Donovan
2B
Donovan is out with groin
Out

Johan Oviedo
SP
Oviedo is questionable with elbow
Questionable
Endy Rodriguez
1B
Rodriguez is out with elbow
Out
Jared Jones
SP
Jones is out with elbow
Out

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PITCHER		PC	IP	K	ER
RC.Mlodzinski, P		46	3	4	1
RB.Chandler, P		44	2.2	2	0

HITTERS	H-AB	R	RBI
1J.Triolo, SS	0-1	1	0
2S.Horwitz, 1B	0-3	1	0
3B.Reynolds, RF	0-3	0	0
4T.Pham, LF	1-3	0	2
5N.Gonzales, 2B	0-3	0	0
6A.McCutchen, DH	0-2	0	0
7O.Cruz, CF	0-3	0	0
8H.Davis, C	0-2	0	0
9I.Kiner-Falefa, 3B	2-2	0	0

PITCHER		PC	IP	K	ER
RS.Gray, P		78	6	5	1

HITTERS	H-AB	R	RBI
1L.Nootbaar, RF	0-1	0	0
2I.Herrera, DH	1-2	0	0
3A.Burleson, LF	0-3	0	0
4W.Contreras, 1B	0-3	0	0
5N.Gorman, 3B	0-3	0	0
6M.Winn, SS	1-2	1	0
7T.Saggese, 2B	0-1	0	0
8P.Pages, C	2-2	0	1
9N.Church, CF	0-2	0	0