Cardinals vs. Guardians Odds & Betting Predictions - June 27, 2025

Cardinals at Guardians

11:10 pm • Apple TV+

Stream Live on SiriusXM - Free 3 Month Offer

St. Louis Cardinals

@

Cleveland Guardians

pitcher		team	era	w-l
L.Ortiz			4.30	4-8
S.Gray			3.72	7-2

MatchupOpenSpreadTotalMoneyline
Cardinals 44-37	-1.5	-1.5+126	o8.5-105	-130
Guardians 40-38	u8.5	+1.5-152	u8.5-115	+110

location pin

Friday 11:10 p.m.

June 27, 2025

Progressive FieldCleveland

thermometer image

85°Fahrenheit

rain image

19%Rain

wind image

8Wind

CLE +110

0.5u

Bet to +103

Over 8.5+100

0.5u

Bet to -110

2 PRO Systems Agree on Friday Pick
Alex Kolodziej•
Jun 26, 2025 UTC

See more MLB Coverage

No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 2-3 in their last 5 games against the spread
Guardians are 22-20 in their road games against the spread
The totals have gone OVER in 2 of Guardians' last 5 games
The totals have gone OVER in 17 of Guardians' 36 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	39-39	17-19	22-20	15-14	24-24
Cardinals	44-37	23-19	21-18	14-21	29-16

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	32-42-4	17-18-1	15-24-3	14-15	18-26-4
Cardinals	43-35-3	23-18-1	20-17-2	20-13-2	22-22-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	40-38	20-16	20-22	19-10	21-27
Cardinals	44-37	26-16	18-21	19-16	24-21

date	opponent	score	spread	over/under	moneyline
Jun 26th	TOR	L 0-6	-1.5 L	U 7.5	TOR -136
Jun 25th	TOR	W 5-4	-1.5 L	O 8	CLE -125
Jun 24th	TOR	L 6-10	+1.5 L	O 9	TOR +112
Jun 22nd	@ATH	W 3-0	-1.5 W	U 9	CLE -113
Jun 22nd	@ATH	W 4-2	-1.5 W	U 9.5	CLE -135

Ben Lively
SP
Lively is out with elbow
Out
Shane Bieber
SP
Bieber is out with elbow
Out
John Means
SP
Means is out with elbow
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RS.Gray, P		7-2	3.72	1.193	9.57

HITTERS	AVG	OBP	SLG	HR
1B.Donovan, 2B	.305	.372	.432	5
2M.Winn, SS	.257	.324	.391	7
3A.Burleson, RF	.298	.333	.460	9
4W.Contreras, 1B	.246	.330	.414	10
5L.Nootbaar, LF	.230	.337	.388	11
6N.Arenado, 3B	.245	.306	.395	10
7N.Gorman, DH	.228	.322	.416	6
8P.Pages, C	.220	.270	.355	5
9V.Scott, CF	.239	.330	.322	3

PITCHER		W-L	ERA	WHIP	K/9
RL.Ortiz, P		4-8	4.30	1.408	10.03

HITTERS	AVG	OBP	SLG	HR
1S.Kwan, LF	.307	.372	.428	6
2K.Manzardo, DH	.221	.301	.447	12
3J.Ramirez, 3B	.318	.378	.516	13
4C.Santana, 1B	.237	.332	.366	9
5L.Thomas, CF	.178	.248	.277	3
6D.Schneemann, 2B	.238	.318	.424	8
7N.Jones, RF	.212	.299	.318	3
8G.Arias, SS	.233	.294	.363	5
9B.Naylor, C	.174	.280	.371	9

Could not load odds

See more MLB Odds

MatchupOverUnder
Cardinals 44-37	N/A	N/A
Guardians 40-38	N/A	N/A