Virginia vs. Louisville Odds & Betting Predictions - October 4, 2025

Virginia at Louisville

4:00 pm

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Virginia Cavaliers

@

Louisville Cardinals

MatchupOpenSpreadTotalMoneyline
Virginia 2-1	N/A	N/A	N/A
Louisville 2-0	N/A	N/A	N/A

location pin

Saturday 4:00 p.m.

October 04, 2025

L&N Federal Credit Union StadiumLouisville

No props found

NCAAF Public Betting

Louisville are 2-0 in their last 5 games.
Louisville are 0-2 in their last 5 games against the spread
The totals have gone OVER in 1 of Louisville' last 2 games
The totals have gone OVER in 1 of Louisville' 2 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Louisville	0-2	0-2	N/A	0-2	N/A
Virginia	2-1	2-0	0-1	2-0	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Louisville	1-1	1-1	N/A	1-1	N/A
Virginia	3-0	2-0	1-0	2-0	1-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Louisville	2-0	N/A	N/A	2-0	N/A
Virginia	2-1	N/A	N/A	2-0	0-1

date	opponent	score	spread	over/under	moneyline
Sep 5th	JMU	W 28-14	-15.5 L	U 56.5	LOU -690
Aug 30th	EKU	W 51-17	-38.5 L	O 56.5	LOU -4875
Dec 31st	@WASH	W 35-34	+1 W	O 50.5	LOU -102
Nov 30th	@UK	W 41-14	-5 W	O 50	LOU -198
Nov 23rd	PITT	W 37-9	-7.5 W	U 57.5	LOU -276

Total

Passing

868

YDS

464

75/114

Comps/Atts

38/60

7.61

YPA

7.73

4/2

TDs/INTs

3/3

0/0

Sacks/Yards

3/18

Rushing

800

Rush Yards

342

127

Attempts

60

6.3

YPC

5.7

12

TDs

5

Turnovers

Fumbles Lost

2

Interceptions

3

Efficiency

15/19 78.9%

Redzone

5/6 83.3%

31/53 0%

3rd Down

11/23 0%

4/9 0%

4th Down

1/2 0%

First Downs

77

Total

39

40

Pass

19

35

Rush

16

2

Penalty

4

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Virginia 2-1	N/A	N/A
Louisville 2-0	N/A	N/A