Dukes vs. Cardinals Odds & Betting Predictions - September 5, 2025
Dukes at Cardinals
11:00 pm • ESPN2Dukes at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Dukes 12-2 | +14.5 | +15.5-110 | o56.5-110 | +490 |
Cardinals 9-4 | u54.5 | -15.5-110 | u56.5-108 | -690 |

L&N Federal Credit Union StadiumLouisville
Dukes vs. Cardinals Expert Picks
Will Brinson
Last 30d: 6-11-0 (-3.2u)
Over 54.5-110
1.1u
Top Shelf Action 🥃
Last 30d: 144-140-1 (-0.9u)
Under 55.5-115
0.87u
💰🦡 Jake
Last 30d: 71-90-4 (-22.1u)
JMU +360 (1H)
1.08u
JMU +8.5 (1H)-110
1u
Analytics Trends
Last 30d: 0-0-0 (+0.0u)
JMU +14.5-108
0.93u
No time for writeup, they may win outright
The Degenerates
Last 30d: 107-93-8 (+6.0u)
JMU +14.5-110
1u
The Pick Don
Last 30d: 10-10-0 (-0.4u)
LOU -14.5-108
1.62u
POTD. Good to 15.5
John Feltman
Last 30d: 67-74-2 (-15.5u)
Over 55-110
2.2u
Big Bets On Campus (CFB)
Last 30d: 31-17-5 (+15.3u)
Over 55.5-105
1u
@_Collin1 https://myaction.app/jBs4sSa5pWb
Allan Lem
Last 30d: 175-136-0 (+12.8u)
L.Ellis u33.5 Rec Yds-115
0.58u
Tailing @MrTuttle05
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
L.Ellis u33.5 Rec Yds-115
1.15u
Brian Bitler
Last 30d: 96-112-1 (-68.2u)
Under 56-112
2.68u
Road to CFB
Last 30d: 6-8-0 (-1.7u)
JMU +410
0.24u
BBOC G5 Deep Dive Pod
Last 30d: 0-0-0 (+0.0u)
JMU +14.5-110
0.91u
@Breese Best Bet 1
Collin Wilson
Last 30d: 15-10-3 (+5.2u)
Over 58.5-110
1.1u
Duck
Last 30d: 83-65-0 (+6.6u)
JMU +14.5-115
0.87u
Ryan Minion
Last 30d: 268-307-4 (-46.2u)
JMU +14.5-110
$1.00
Mike Calabrese
Last 30d: 48-43-2 (+8.1u)
JMU +14.5-108
1.62u
Bob Chesney is not only a winner, but a guy who doesn’t get blown out. In his last 46 games as a head coach, he’s lost by more than 14 points one time. And that came at South Dakota State in the FCS Playoffs, the Jackrabbits won the FCS Natty that year. That’s a long, long run of being prepared when you’re playing up, playing down, sandwich spots, lookaheads, there are no traps with Chesney at the helm. #GoDukes 🟣🐶
Dukes vs. Cardinals Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Dukes vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 3-2 in their last 5 games.
- Cardinals are 2-3 in their last 5 games against the spread
- Cardinals are 3-1 in their road games against the spread
- The totals have gone OVER in 2 of Cardinals' last 5 games
- The totals have gone OVER in 4 of Cardinals' 8 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
137
YDS
151
18/31
Comps/Atts
13/23
4.419354838709677
YPA
6.565217391304348
1/1
TDs/INTs
1/0
6/28
Sacks/Yards
3/18
Dukes vs. Cardinals Odds Comparison
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Dukes at Cardinals Team Totals
MatchupOverUnder | ||
|---|---|---|
Dukes 12-2 | o20.5-110 | u20.5-117 |
Cardinals 9-4 | o36.5-112 | u36.5-114 |






