Guardians vs. Twins Odds & Betting Predictions - May 21, 2025

Guardians at Twins

5:10 pm • CLEG

Cleveland Guardians

5

5 - 6

Minnesota Twins

6

pitcher		team	era	w-l
B.Ober			3.68	4-1
L.Allen			3.86	2-2

MatchupOpenSpreadTotalMoneyline
Guardians 26-22	+1.5	+1.5+105	o11.5-120	+125
Twins 27-22	u6.5	-1.5-139	u11.5-115	-154

location pin

Wednesday 5:10 p.m.

May 21, 2025

Target FieldMinneapolis

MIN -110

1u

3 MLB Player Props for Wednesday
Doug Ziefel•
May 21, 2025 UTC

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MLB Public Betting

Twins are 3-2 in their last 5 games.
Twins are 2-3 in their last 5 games against the spread
Twins are 13-13 in their road games against the spread
The totals have gone OVER in 0 of Twins' last 5 games
The totals have gone OVER in 7 of Twins' 23 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Twins	28-21	15-8	13-13	17-14	11-7
Guardians	22-26	11-11	11-15	9-10	13-15

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Twins	16-30-3	7-15-1	9-15-2	10-19-2	6-11-1
Guardians	21-24-3	8-13-1	13-11-2	11-8	10-15-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Twins	27-22	16-7	11-15	18-13	9-9
Guardians	26-22	14-8	12-14	13-6	13-15

date	opponent	score	spread	over/under	moneyline
May 18th	@MIL	L 2-5	+1.5 L	U 7.5	MIL +123
May 17th	@MIL	W 7-0	-1.5 W	U 7.5	MIN -125
May 17th	@MIL	W 3-0	-1.5 W	U 7.5	MIN -120
May 15th	@BAL	W 4-0	+1.5 W	U 9	MIN +112
May 14th	@BAL	W 8-6	+1.5 W	O 9	MIN +120

Shane Bieber
SP
Bieber is out with elbow
Out
John Means
SP
Means is out with elbow
Out
David Fry
C
Fry is out with elbow
Out

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PITCHER		PC	IP	K	ER
LL.Allen, P		53	3	3	2
RJ.Junis, P		41	1.2	0	2
LJ.Cantillo, P		43	2.1	4	0
LK.Allard, P		22	1	1	1
RC.Smith, P		15	0.2	0	1

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	1-4	0	0	0
2A.Martinez, 2B	1-4	1	0	0
2A.Martinez, CF	1-4	1	0	0
3J.Ramirez, 3B	1-4	1	0	0
4K.Manzardo, DH	1-3	0	0	1
5C.Santana, 1B	1-4	2	1	1
6N.Jones, CF	1-4	1	0	1
6N.Jones, RF	1-4	1	0	1
7G.Arias, SS	0-4	0	0	0
8B.Naylor, C	1-4	0	0	2
9W.Brennan, RF	1-2	0	0	0
9D.Schneemann, PH	0-1	0	0	0
9D.Schneemann, 2B	0-1	0	0	0

PITCHER		PC	IP	K	ER
RB.Ober, P		42	3	3	1
RJ.Ryan, P		89	5	4	3
RJ.Duran, P		23	1	1	1

HITTERS	H-AB	R	HR	RBI
1R.Jeffers, C	1-2	1	0	0
2B.Lee, SS	0-4	0	0	0
3R.Lewis, DH	1-4	0	0	0
4T.France, 1B	1-4	0	0	1
4R.Fitzgerald, PR	0-0	1	0	0
5T.Larnach, LF	2-4	1	0	0
5T.Larnach, RF	2-4	1	0	0
5D.Keirsey, PR	0-1	1	0	0
5D.Keirsey, LF	0-1	1	0	0
6J.Bride, 3B	3-5	0	0	0
7C.McCusker, RF	0-1	0	0	0
7K.Clemens, PH	2-3	1	0	2
7K.Clemens, 2B	2-3	1	0	2
8H.Bader, CF	1-3	1	0	2
9W.Castro, 2B	1-3	0	0	1
9W.Castro, LF	1-3	0	0	1
9W.Castro, RF	1-3	0	0	1

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MatchupOverUnder
Guardians 26-22	N/A	N/A
Twins 27-22	N/A	N/A