Astros vs. Athletics Odds & Betting Predictions - September 24, 2025

Astros at Athletics

2:05 am • SCHN
1 - 5
Starting Pitchers
pitcherteameraw-l
Jeffrey Springs logoJ.SpringsAthletics logo4.1111-11
Cristian Javier logoC.JavierHouston Astros logo4.622-4

Astros at Athletics Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
84-73
-1.5
-1.5+150
o10-109
-104
Athletics
74-83
u10.5
+1.5-176
u10-110
-116
location pinWednesday 2:05 a.m.
September 24, 2025
Sutter Health ParkWest Sacramento
Astros vs. Athletics Expert Picks
Wags Wins
Wags Wins
Last 30d: 158-138-1 (+9.1u)
Over 9.5-122
1.5u
The Degenerates
The Degenerates
Last 30d: 71-76-2 (-12.8u)
HOU -108
1.08u
Picks Office
Picks Office
Last 30d: 62-87-4 (-21.4u)
HOU +100
1u
Grant Neiffer
Grant Neiffer
Last 30d: 42-145-11 (+1.9u)
I.Paredes o0.5 HR+450
0.25u
J.Altuve o0.5 HR+475
0.25u
C.Walker o0.5 HR+360
0.25u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 63-75-4 (+1.6u)
ATH -104
0.96u
Matt DiLeo
Matt DiLeo
Last 30d: 38-35-0 (-2.9u)
J.Springs u5.5 Hits Allowed-117
0.85u
Lines at Lunch
Lines at Lunch
Last 30d: 94-82-2 (+8.3u)
N.Kurtz o1.5 Total Bases-110
1u
Ryan Sura
Ryan Sura
Last 30d: 88-80-2 (+11.1u)
N.Kurtz o1.5 Total Bases-110
1u
Brian Bitler
Brian Bitler
Last 30d: 86-81-0 (+9.5u)
ATH -105
2.86u
Sean Zerillo
Sean Zerillo
Last 30d: 160-171-4 (-4.8u)
ATH -110
0.5u
Bet to -120

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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Athletics Public Betting Percentages

Away Logo

Astros

Public

63%

Bets%

37%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Athletics
84-7337-3947-3414-2368-48
Astros
79-7837-4442-3440-5839-18

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Athletics
75-74-838-36-237-38-614-21-259-51-6
Astros
71-79-736-43-235-36-544-52-225-27-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Athletics
74-8334-4240-4117-2054-62
Astros
84-7346-3538-3853-4531-26

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 21st@PITL 0-11-1.5 LO 8.5PIT +100
Sep 20th@PITL 0-2-1.5 LU 8PIT -113
Sep 19th@PITW 4-3-1.5 LU 8.5ATH -112
Sep 18th@BOSW 5-3+1.5 WU 9ATH +126
Sep 17th@BOSL 4-5+1.5 WU 9BOS +140

Athletics vs. Astros Injury Updates

Athletics Injuries

  • Luis Medina
    SP

    Medina is out with elbow

    Out

  • Brady Basso
    RP

    Basso is out with shoulder

    Out

Astros Injuries

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

Astros vs. Athletics Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Cristian Javier logoRC.Javier, P794.243
Jayden Murray logoRJ.Murray, P261.110
Steven Okert logoLS.Okert, P11110
Enyel De Los Santos logoRE.De Los Santos, P19111
HITTERSH-ABRHRRBI
Jose Altuve logo1J.Altuve, 2B0-4000
Carlos Correa logo2C.Correa, 3B0-2000
Carlos Correa logo2C.Correa, SS0-2000
Isaac Paredes logo3I.Paredes, DH0-4000
Christian Walker logo4C.Walker, 1B2-4100
Yainer Diaz logo5Y.Diaz, C1-4000
Jake Meyers logo6J.Meyers, CF0-3000
Zach Cole logo7Z.Cole, LF0-3000
Zach Cole logo7Z.Cole, RF0-3000
Cam Smith logo8C.Smith, RF0-1001
Jesus Sanchez logo8J.Sanchez, PH0-1000
Jesus Sanchez logo8J.Sanchez, LF0-1000
Mauricio Dubon logo9M.Dubon, SS0-2000
Victor Caratini logo9V.Caratini, PH0-0000
Ramon Urias logo9R.Urias, 3B0-0000
Athletics Player Stats
Projected
PITCHERPCIPKER
Jeffrey Springs logoLJ.Springs, P81531
Tyler Ferguson logoRT.Ferguson, P25220
Justin Sterner logoRJ.Sterner, P16100
Michael Kelly logoRM.Kelly, P9110
HITTERSH-ABRHRRBI
Nick Kurtz logo1N.Kurtz, 1B1-4100
Shea Langeliers logo2S.Langeliers, C1-4000
Tyler Soderstrom logo3T.Soderstrom, LF2-4101
Brent Rooker logo4B.Rooker, DH0-3000
Jacob Wilson logo5J.Wilson, SS2-2201
Lawrence Butler logo6L.Butler, CF1-4000
Darell Hernaiz logo7D.Hernaiz, 2B1-3001
Carlos Cortes logo8C.Cortes, RF0-3001
Brett Harris logo9B.Harris, 3B1-4100

Astros vs. Athletics Odds Comparison

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Astros at Athletics Team Totals

MatchupOverUnder
Astros
84-73
o4.5-137
u4.5+108
Athletics
74-83
o4.5-127
u4.5-102