Athletics vs. Pirates Odds & Betting Predictions - September 21, 2025

Athletics at Pirates

5:35 pm • NBCS-CA

Athletics

0

0 - 11

Pittsburgh Pirates

11

pitcher		team	era	w-l
M.Burrows			3.93	2-4
M.Spence			4.96	3-6

MatchupOpenSpreadTotalMoneyline
Athletics 74-83	+1.5	-1.5+172	o8.5-108	+100
Pirates 68-89	u8.5	+1.5-193	u8.5-113	-121

location pin

Sunday 5:35 p.m.

September 21, 2025

PNC ParkPittsburgh

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MLB Public Betting

Pirates are 3-2 in their last 5 games.
Pirates are 4-1 in their last 5 games against the spread
Pirates are 38-38 in their road games against the spread
The totals have gone OVER in 2 of Pirates' last 5 games
The totals have gone OVER in 33 of Pirates' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	86-71	48-33	38-38	19-26	65-44
Athletics	84-73	37-39	47-34	14-23	68-48

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	60-89-8	33-43-5	27-46-3	17-26-2	41-62-6
Athletics	75-74-8	38-36-2	37-38-6	14-21-2	59-51-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	68-89	44-37	24-52	22-23	45-64
Athletics	74-83	34-42	40-41	17-20	54-62

date	opponent	score	spread	over/under	moneyline
Sep 20th	ATH	W 2-0	+1.5 W	U 8	PIT -107
Sep 19th	ATH	L 3-4	+1.5 W	U 8.5	ATH -107
Sep 17th	CHC	L 4-8	+1.5 L	O 7.5	CHC +121
Sep 16th	CHC	L 1-4	-1.5 L	U 6.5	CHC -131
Sep 15th	CHC	L 0-4	+1.5 L	U 8	CHC +102

Luis Medina
SP
Medina is out with elbow
Out
Brady Basso
RP
Basso is out with shoulder
Out

Johan Oviedo
SP
Oviedo is questionable with elbow
Questionable
Joey Bart
C
Joey Bart scratched Tuesday.
Out
Endy Rodriguez
1B
Rodriguez is out with elbow
Out
Jared Jones
SP
Jones is out with elbow
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RM.Spence, P		64	3.1	1	6
RO.Bido, P		63	3.2	6	3
RS.McGough, P		24	1	1	1

HITTERS	H-AB	R	HR	RBI
1L.Butler, CF	0-3	0	0	0
1C.Thomas, CF	0-1	0	0	0
2B.Rooker, DH	2-4	0	0	0
3N.Kurtz, 1B	1-3	0	0	0
3B.Harris, 1B	1-1	0	0	0
4T.Soderstrom, LF	1-2	0	0	0
4J.Bleday, PH	0-2	0	0	0
4J.Bleday, LF	0-2	0	0	0
5J.Wilson, SS	0-4	0	0	0
5M.Muncy, 3B	0-0	0	0	0
6C.Cortes, RF	1-4	0	0	0
7D.Hernaiz, 3B	0-4	0	0	0
7D.Hernaiz, SS	0-4	0	0	0
8W.MacIver, C	1-4	0	0	0
9M.Schuemann, 2B	1-3	0	0	0

PITCHER		PC	IP	K	ER
RM.Burrows, P		74	4	3	0
RC.Mlodzinski, P		48	3	3	0
RY.Ramirez, P		13	1	1	0
RD.Moreta, P		15	1	2	0

HITTERS	H-AB	R	HR	RBI
1O.Cruz, CF	1-5	1	0	2
2J.Triolo, 3B	4-5	2	1	3
2C.Devanney, 3B	0-0	0	0	0
3B.Reynolds, RF	1-3	1	0	0
3A.Canario, RF	1-1	0	0	0
4S.Horwitz, 1B	0-3	1	0	1
5A.McCutchen, DH	1-4	1	0	1
6N.Gonzales, SS	1-4	0	0	1
7J.Suwinski, LF	1-4	1	0	0
8J.Bart, C	4-4	2	1	3
9N.Yorke, 2B	1-4	2	0	0

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MatchupOverUnder
Athletics 74-83	o3.5-141	u3.5+111
Pirates 68-89	o4-116	u4-110