Turn your sports knowledge into winning predictions
21+ or 18+ in Certain Locations. 19+ in ON. Please Play Responsibly. Gambling Problem? Call 1-800-GAMBLER. Visit connexontario.ca or Call 1-866-531-2600 in ON.
No Code Needed

Illinois vs. Duke Odds & Betting Predictions - September 6, 2025

Illinois at Duke

4:00 pm • ESPN

Illinois Fighting Illini

3-0
45
45 - 19

Duke Blue Devils

1-2
19

Illinois at Duke Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Illinois
3-0
-2.5
-2.5-108
o49-110
-134
Duke
1-2
u49.5
+2.5-112
u49-110
+114
location pinSaturday 4:00 p.m.
September 06, 2025
Brooks Field at Wallace Wade StadiumDurham
Illinois vs. Duke Expert Picks
Sir Lockselot
Sir Lockselot
Last 30d: 26-63-0 (-51.0u)
DUKE +114
3u
📚Player Profit 🔑 Duke ML +114 (Player Profit) 3u Mensah > Altmyer. Amazing value at home for what I think is the more talented team. Illinois struggles on the road generally. Go blue devils! Code: sirlocks for 10% off every deposit at playerprofit.com
Vegas Refund
Vegas Refund
Last 30d: 23-21-0 (-0.4u)
DUKE +2.5-105
1.05u
Sandy Plashkes
Sandy Plashkes
Last 30d: 60-84-2 (-25.0u)
DUKE +2.5-110
1.1u
Sean Zerillo
Sean Zerillo
Last 30d: 180-198-4 (-5.1u)
Over 48.5-110
0.25u
Mjaybrod
Mjaybrod
Last 30d: 32-45-0 (-15.9u)
DUKE +3-110
1u
Outright for the blue devils
Firefighter Bets
Firefighter Bets
Last 30d: 146-139-0 (+0.3u)
DUKE +2.5-110
1u
Big Bets On Campus (CFB)
Big Bets On Campus (CFB)
Last 30d: 47-40-1 (+5.1u)
DUKE o23.5 Team Total-110
1u
@_Collin1 https://myaction.app/jBs4sSa5pWb
DUKE +3-105
1u
@Stuckey2 @_Collin1 https://myaction.app/jBs4sSa5pWb
Brian Bitler
Brian Bitler
Last 30d: 100-89-0 (+25.1u)
DUKE +2.5+105
3u
Stuck 🚨
Stuck 🚨
Last 30d: 36-32-1 (-0.0u)
DUKE +3-105
0.4u
Collin Wilson
Collin Wilson
Last 30d: 68-40-5 (+20.5u)
DUKE +3-108
1.08u
Backing Darian Mensah v Illinois 3-3-5. Altmyer still breaking in new targets. Both teams flawless box scores in Week 1
Brian Bitler
Brian Bitler
Last 30d: 100-89-0 (+25.1u)
DUKE +3-108
3u
DeadPresPicks
DeadPresPicks
Last 30d: 14-24-0 (-3.2u)
DUKE +3-110
0.75u
Ryan Sura
Ryan Sura
Last 30d: 71-71-3 (+0.2u)
DUKE +3-106
1.06u

Illinois vs. Duke Previews & Analysis

  • Illinois vs. Duke: Early And Often article feature image

    Illinois vs. Duke: Early And Often

    Doug Ziefel•
    Sep 6, 2025 UTC
  • Expert College Football Picks For Week 2! | College Football Best Bets & Props On BBOC article feature image

    Expert College Football Picks For Week 2! | College Football Best Bets & Props On BBOC

    Mike Calabrese•
    Sep 6, 2025 UTC
  • Collin Wilson's Week 2 ML Round Robin article feature image

    Collin Wilson's Week 2 ML Round Robin

    Collin Wilson•
    Sep 5, 2025 UTC
  • Stuckey & Wilson: Our Top ML Dogs for Week 2 article feature image

    Stuckey & Wilson: Our Top ML Dogs for Week 2

    Collin Wilson•
    Sep 5, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Illinois vs. Duke Public Betting Percentages

Away Logo

Illinois

Public

Home Logo

Duke

37%

Bets%

63%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Duke are 1-2 in their last 5 games.
  • Duke are 0-3 in their last 5 games against the spread
  • Duke are 0-1 in their road games against the spread
  • The totals have gone OVER in 3 of Duke' last 3 games
  • The totals have gone OVER in 2 of Duke' 2 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Duke		0-30-20-10-10-2
Illinois		3-02-01-02-0N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Duke		3-02-01-01-02-0
Illinois		1-20-21-01-1N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Duke		1-2N/AN/A1-00-2
Illinois		3-0N/AN/A2-0N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 28thELOW 45-17-36.5 LO 51-
Jan 3rd@MISSL 20-52+18.5 LO 51.5MISS +650
Nov 30th@WFW 23-17-3.5 WU 53.5DUKE -165
Nov 24thVTW 31-28+2.5 WO 45.5DUKE +114
Nov 9th@NCSTW 29-19+3.5 WU 51.5DUKE +128
Team Stats

Total

419
Total Yards
438
73
Total Plays
63
5.739726027397261
Yards Per Play
6.9523809523809526

Passing

296
YDS
356
22/31
Comps/Atts
25/39
9.548387096774194
YPA
9.128205128205128
3/0
TDs/INTs
2/1
4/29
Sacks/Yards
2/7

Rushing

123
Rush Yards
82
42
Attempts
24
2.9285714285714284
YPC
3.4166666666666665
3
TDs
0

Turnovers

0
Fumbles Lost
4
0
Interceptions
1

Efficiency

5/5 100%
Redzone
3/4 75%
5/13 0%
3rd Down
4/10 0%
2/2 0%
4th Down
1/2 0%

First Downs

25
Total
21
13
Pass
14
8
Rush
5
4
Penalty
2

Misc

7/51
Penalties/Yards
6/69

Illinois vs. Duke Odds Comparison

Right Arrow

Could not load odds

See more NCAAF Odds Right Arrow

Illinois at Duke Team Totals

MatchupOverUnder
Illinois
3-0
o25-111
u25-114
Duke
1-2
o23.5-125
u23.5-106