Pittsburgh vs. Syracuse Odds & Betting Predictions - October 18, 2025

Pittsburgh at Syracuse

11:30 pm • ACC Network

Pittsburgh Panthers

30

30 - 13

Syracuse Orange

13

MatchupOpenSpreadTotalMoneyline
Pittsburgh 6-2	-11.5	-9.5-110	o54.5-112	-355
Syracuse 3-5	u55.5	+9.5-110	u54.5-108	+280

location pin

Saturday 11:30 p.m.

October 18, 2025

JMA Wireless DomeSyracuse

SYR +9.5-110

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NCAAF Public Betting

Syracuse are 2-3 in their last 5 games.
Syracuse are 3-2 in their last 5 games against the spread
Syracuse are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Syracuse' last 5 games
The totals have gone OVER in 1 of Syracuse' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Syracuse	3-4-1	1-2-1	2-1	0-0-1	2-4
Pittsburgh	6-2	4-1	2-1	4-1	1-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Syracuse	4-4	1-3	2-1	0-1	3-3
Pittsburgh	6-2	5-0	1-2	3-2	2-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Syracuse	3-5	N/A	N/A	1-0	1-5
Pittsburgh	6-2	N/A	N/A	4-1	1-1

date	opponent	score	spread	over/under	moneyline
Oct 4th	@SMU	L 18-31	+17.5 W	U 57	SMU +575
Sep 27th	DUKE	L 3-38	+4.5 L	U 55.5	DUKE +155
Sep 20th	@CLEM	W 34-21	+17.5 W	O 53.5	SYR +600
Sep 12th	CGT	W 66-24	-36.5 W	O 64.5	-
Sep 6th	UCONN	W 27-20	-7 L	U 57.5	SYR -275

Total

217

Total Yards

217

55

Total Plays

57

3.9454545454545453

Yards Per Play

3.807017543859649

Passing

111

YDS

126

11/22

Comps/Atts

16/27

5.045454545454546

YPA

4.666666666666667

0/1

TDs/INTs

2/3

7/35

Sacks/Yards

1/12

Rushing

106

Rush Yards

91

33

Attempts

30

3.212121212121212

YPC

3.033333333333333

1

TDs

0

Turnovers

0

Fumbles Lost

0

1

Interceptions

3

Efficiency

3/3 100%

Redzone

2/2 100%

2/12 0%

3rd Down

4/14 0%

0/0 0%

4th Down

1/1 0%

First Downs

13

Total

12

5

Pass

4

7

Rush

6

1

Penalty

2

Misc

10/84

Penalties/Yards

8/75

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MatchupOverUnder
Pittsburgh 6-2	o31.5-113	u31.5-114
Syracuse 3-5	o22-120	u22-110