Syracuse vs Clemson Odds & Live Scores - September 20, 2025

Syracuse at Clemson

4:00 pm • ESPN

Syracuse Orange

1-2

34 - 21

Clemson Tigers

3-1

MatchupOpenSpreadTotalMoneyline
Syracuse 1-2	+16.5	+17.5-108	o53.5-112	+600
Clemson 3-1	u55.5	-17.5-112	u53.5-110	-900

Saturday 4:00 p.m.

September 20, 2025

Memorial Stadium (Clemson, SC)Clemson

CLEM +7.5 (Live)-115

1.15u

SYR +17.5-110

A.Williams u54.5 Rec Yds-114

1.01u

C.Klubnik o268.5 Pass Yds-110

1.05u

CLEM -16.5-118

1.25u

CLEM -17-110

CLEM -16.5-115

0.25u

Boyd / FanDuel

CLEM -3.5 (1Q)-128

6.4u

CLEM -17-108

1.1u

CLEM -9.5 (1H)-115

1.15u

T.Moore o3.5 Recs+120

1.2u

SYR +18-110

0.5u

CLEM -17+100

Under 56.5-110

0.5u

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NCAAF Public Betting

Clemson are 3-1 in their last 5 games.
Clemson are 2-2 in their last 5 games against the spread
Clemson are 1-1 in their road games against the spread
The totals have gone OVER in 2 of Clemson' last 4 games
The totals have gone OVER in 1 of Clemson' 2 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson	2-2	1-1	1-1	2-1	0-1
Syracuse	1-2	1-1	0-1	1-1	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson	2-2	1-1	1-1	1-2	1-0
Syracuse	1-2	1-1	0-1	1-1	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson	3-1	N/A	N/A	3-0	0-1
Syracuse	1-2	N/A	N/A	1-1	0-1

date	opponent	score	spread	over/under	moneyline
Sep 13th	@GT	L 21-24	-3 L	U 50.5	GT -145
Sep 6th	TROY	W 27-16	-30.5 L	U 51.5	CLEM -11946
Aug 30th	LSU	L 10-17	-5 L	U 55.5	LSU -205
Dec 21st	@TEX	L 24-38	+13.5 L	O 49.5	TEX +470
Dec 8th	@SMU	W 34-31	+2.5 W	O 56.5	CLEM +111

Syracuse

Total

Clemson

433

Total Yards

503

Total Plays

5.623376623376624

Yards Per Play

6.0602409638554215

Syracuse

Passing

Clemson

278

YDS

363

21/39

Comps/Atts

37/61

7.128205128205129

YPA

5.950819672131147

3/0

TDs/INTs

3/1

3/11

Sacks/Yards

1/1

Syracuse

Rushing

Clemson

155

Rush Yards

140

Attempts

4.078947368421052

YPC

6.363636363636363

TDs

Syracuse

Turnovers

Clemson

Fumbles Lost

Interceptions

Syracuse

Efficiency

Clemson

4/4 100%

Redzone

2/2 100%

3/15 0%

3rd Down

3/13 0%

2/2 0%

4th Down

1/5 0%

Syracuse

First Downs

Clemson

Total

Pass

Rush

Penalty

Syracuse

Misc

Clemson

7/52

Penalties/Yards

8/75

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See more NCAAF Odds

MatchupOverUnder
Syracuse 1-2	N/A	N/A
Clemson 3-1	N/A	N/A

Syracuse vs. Clemson Odds & Betting Predictions - September 20, 2025

Syracuse at Clemson

Syracuse Orange

Clemson Tigers

Syracuse at Clemson Odds

Spread, Total, Moneyline

Syracuse vs. Clemson Previews & Analysis

5 Star QBs, 5 Player Prop Picks

Syracuse vs. Clemson: Should You Target Total?

Our NCAAF Best Bets for Saturday's Noon Games

Your Week 4 NCAAF Betting Cheat Sheet

Prop Odds Comparison

Line Movement Tracker

Syracuse vs. Clemson Public Betting Percentages

Syracuse

Public

Clemson

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

Syracuse vs. Clemson Odds Comparison

Syracuse at Clemson Team Totals