Athletics vs. Astros Odds & Betting Predictions - May 28, 2025

Athletics at Astros

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Starting Pitchers
pitcherteameraw-l
Hunter Brown logoH.BrownHouston Astros logo0.000-0
JP Sears logoJ.SearsAthletics logo0.000-0

Athletics at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Athletics
23-31
+1.5
+1.5-110
o8-115
+198
Astros
28-25
u7.5
-1.5-110
u8-105
-242
location pinWednesday 12:10 a.m.
May 28, 2025
Daikin ParkHouston
thermometer image84°Fahrenheit
rain image0%Rain
wind image6Wind
Athletics vs. Astros Expert Picks
💰🦡 Jake
💰🦡 Jake
Last 30d: 92-102-6 (-5.6u)
Over 4 (F5)-120
1.2u
Grant Neiffer
Grant Neiffer
Last 30d: 32-127-6 (+20.3u)
S.Langeliers o0.5 HR+650
0.5u
B.Rooker o0.5 HR+575
0.5u
Picks Office
Picks Office
Last 30d: 68-79-3 (-14.8u)
HOU -1.5+105
1u
Astros get Hunter Brown on the bump – 2.04 ERA, 0.91 WHIP across 10 starts. Bounce-back spot after rare bad outing. Astros 7-1 last 8 vs A’s at Daikin after a win. Houston 9-2 on run line vs AL West teams under .500. Oakland just 1 win in last 10. Bad spot. JP Sears? Brutal May – 0-2, 5.75 ERA, 1.28 WHIP. Last 2 starts: 10 ER, 5 HR allowed. Astros top 10 in home scoring – should feast. A’s bullpen no help – team ERA ranks 28th, WHIP 28th or worse. Houston likely builds early lead and runs away late. A’s failed to cover in last 5 night games vs AL teams. Astros pitching staff ranks 8th in ERA, 2nd in WHIP – bullpen can lock it down. Sears gave up 4 HRs last start. Astros should cash early and cover late. Not just a win – expect a clean -1.5 cover.
Billy Ward
Billy Ward
Last 30d: 30-44-6 (-17.2u)
Under 0.5 (1st Inn)-120
1.2u
Jim Sannes
Jim Sannes
Last 30d: 35-48-0 (+7.3u)
H.Brown u6.5 Ks-102
1u
I adore Hunter Brown and am expecting his dominant start to continue -- this is just a bad matchup. The A's active roster has just an 18.0% strikeout rate against righties this year. That pushes my projection on Brown down to 5.75 strikeouts.

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Prop Odds Comparison

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Line Movement Tracker

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Athletics vs. Astros Public Betting Percentages

Away Logo

Athletics

Public

12%

Bets%

88%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros
29-2416-1213-1215-1914-4
Athletics
26-2811-1715-116-1120-16

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros
21-30-211-1710-13-217-173-13-2
Athletics
28-22-418-1010-12-48-7-220-14-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros
28-2518-1010-1518-1610-8
Athletics
23-319-1914-128-914-22

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 25thSEAW 5-3+1.5 WU 8.5HOU +124
May 24thSEAW 2-1+1.5 WU 7HOU -108
May 24thSEAL 3-5+1.5 LU 8.5SEA -122
May 23rdSEAW 9-2+1.5 WO 8HOU +110
May 21st@TBL 4-8-1.5 LO 8.5TB -168

Athletics vs. Astros Injury Updates

Athletics Injuries

  • Luis Medina
    P

    Medina is out with elbow

    Out

  • J.T. Ginn
    P

    Ginn is out with elbow

    Out

  • Ken Waldichuk
    P

    Waldichuk is out with elbow

    Out

  • Zack Gelof
    IF

    Gelof is out with hand

    Out

  • Brett Harris
    IF

    Harris is out with oblique

    Out

  • Brady Basso
    P

    Basso is out with shoulder

    Out

  • Nick Kurtz
    IF

    Kurtz is out with hip

    Out

Astros Injuries

  • Taylor Trammell
    OF

    Trammell is out with calf

    Out

  • Cristian Javier
    P

    Javier is out with elbow

    Out

  • Luis Garcia
    P

    Garcia is out with elbow

    Out

  • Pedro Leon
    OF

    Leon is out with knee

    Out

  • J.P. France
    P

    France is out with shoulder

    Out

  • Hayden Wesneski
    P

    Wesneski is out with elbow

    Out

  • Spencer Arrighetti
    P

    Arrighetti is out with thumb

    Out

Athletics vs. Astros Odds Comparison

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Athletics at Astros Team Totals

MatchupOverUnder
Athletics
23-31
N/A
N/A
Astros
28-25
N/A
N/A