Guardians vs. Diamondbacks Odds & Betting Predictions - August 20, 2025

Guardians at Diamondbacks

1:40 am • MLB Network

Cleveland Guardians

64-61

5 - 6

Arizona Diamondbacks

61-66

pitcher		team	era	w-l
E.Rodriguez			5.40	5-7
T.Bibee			4.62	9-9

MatchupOpenSpreadTotalMoneyline
Guardians 64-61	+1.5	-1.5+319	o8.5-121	+100
Diamondbacks 61-66	u9	+1.5-190	u8.5-101	-120

Wednesday 1:40 a.m.

August 20, 2025

Chase FieldPhoenix

ARI -115

1.74u

Arizona has the edge tonight with Tanner Bibee’s biggest weakness exposed. He’s giving up 1.45 HR/9, and Chase Field doesn’t forgive mistakes. One swing from the D-backs middle order can flip this game fast. That’s the cleanest path to a home win. Eduardo Rodríguez isn’t perfect with a 5.40 ERA, but his strikeout punch at 9.08 K/9 gives him the tools to strand runners when needed. If he limits traffic early, he can hand this game to Arizona’s bullpen with a lead, which is all the D-backs need. Series urgency also matters. Arizona already dropped Game 1 and can’t afford to fall behind at home. With the roof closed, no weather randomness plays in. Execution wins, and the D-backs have the power bats and strikeout arm to even this series.

Under 9-120

@Zerillo

Under 9-110

0.55u

Projecting this closer to 8

Under 9-102

0.51u

Bet to -112

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MLB Public Betting

Diamondbacks are 1-4 in their last 5 games.
Diamondbacks are 1-4 in their last 5 games against the spread
Diamondbacks are 32-32 in their road games against the spread
The totals have gone OVER in 2 of Diamondbacks' last 5 games
The totals have gone OVER in 30 of Diamondbacks' 62 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Diamondbacks	61-65	29-33	32-32	32-45	29-20
Guardians	64-61	28-34	36-27	27-28	37-31

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Diamondbacks	62-59-5	30-28-4	32-31-1	38-35-4	24-24-1
Guardians	56-64-5	31-29-2	25-35-3	29-25-1	26-38-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Diamondbacks	61-66	31-31	30-34	39-38	22-27
Guardians	64-61	31-31	33-30	34-21	30-38

date	opponent	score	spread	over/under	moneyline
Aug 19th	CLE	L 1-3	+1.5 L	U 9	CLE -123
Aug 17th	@COL	L 5-6	-1.5 L	U 12	COL -155
Aug 17th	@COL	L 7-10	-1.5 L	O 11.5	COL -175
Aug 16th	@COL	L 3-4	-1.5 L	U 12	COL -199
Aug 15th	@COL	W 8-2	-1.5 W	U 13	ARI -175

Ben Lively
SP
Lively is out with elbow
Out
John Means
SP
Means is out with elbow
Out

John Curtiss
RP
Curtiss is out with elbow
Out

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PITCHER	PC	IP	K	ER
RT.Bibee, P	92	5.2	5	4
LE.Sabrowski, P	4	0.1	0	0
LT.Herrin, P	12	0.2	0	2
RN.Enright, P	7	0.1	0	0
RJ.Junis, P	8	1	1	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-4	0	0	0
2A.Martinez, CF	2-5	1	0	0
3J.Ramirez, 3B	1-3	2	1	2
4D.Fry, DH	0-2	0	0	0
4K.Manzardo, PH	0-2	0	0	0
4K.Manzardo, DH	0-2	0	0	0
5C.Santana, 1B	1-5	1	0	1
6G.Arias, SS	1-4	1	0	0
7N.Jones, RF	2-4	0	0	1
8B.Rocchio, 2B	0-3	0	0	0
9A.Hedges, C	1-3	0	0	1
9B.Naylor, PR	0-0	0	0	0
9B.Naylor, C	0-0	0	0	0

PITCHER	PC	IP	K	ER
LE.Rodriguez, P	96	6.2	4	4
RJ.Burgos, P	4	0.1	0	0
RA.Hoffmann, P	22	0.2	0	1
LK.Backhus, P	11	0.1	0	0
LA.Saalfrank, P	9	1	1	0

HITTERS	H-AB	R	HR	RBI
1G.Perdomo, SS	2-3	2	0	1
2K.Marte, 2B	0-3	0	0	0
3C.Carroll, RF	2-4	2	0	1
4L.Gurriel, DH	1-4	0	0	3
5P.Smith, 1B	1-4	0	0	0
6B.Alexander, 3B	0-3	0	0	0
7J.McCarthy, LF	2-4	1	1	1
8A.Thomas, CF	1-4	1	0	0
9J.Herrera, C	0-3	0	0	0