Guardians vs. Nationals Odds & Betting Predictions - May 6, 2025

Guardians at Nationals

7:35 pm • MASN2
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Starting Pitchers
pitcherteameraw-l
Jake Irvin logoJ.IrvinWashington Nationals logo4.012-1
Luis L. Ortiz logoL.OrtizCleveland Guardians logo4.782-3

Guardians at Nationals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
20-14
-1.5
-1.5+137
o9-122
-120
Nationals
16-19
u9
+1.5-164
u9+100
+100
location pinTuesday 7:35 p.m.
May 06, 2025
Nationals ParkWashington
thermometer image74°Fahrenheit
rain image0%Rain
wind image13Wind
Guardians vs. Nationals Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 106-122-16 (-14.7u)
CLE -110 (F5)
1.1u
Boomer Betz
Boomer Betz
Last 30d: 171-175-4 (+52.2u)
J.Ramirez o0.5 HR+350
0.1u
Day1
Austin Pendergrass
Austin Pendergrass
Last 30d: 85-129-2 (-35.2u)
J.Wood o0.5 HR+720
0.25u
Profit boost
Grant Neiffer
Grant Neiffer
Last 30d: 34-114-8 (+27.9u)
J.Wood o0.5 HR+480
0.5u
Boomer Betz
Boomer Betz
Last 30d: 171-175-4 (+52.2u)
CLE -115
1u
Cam Is Money
Cam Is Money
Last 30d: 109-109-5 (-2.5u)
CLE -118
1u
DeadPresPicks
DeadPresPicks
Last 30d: 54-44-3 (+10.1u)
WSH -104 (F5)
0.55u

Guardians vs. Nationals Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Nationals Public Betting Percentages

Away Logo

Guardians

Public

63%

Bets%

37%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Nationals
18-1710-68-112-416-13
Guardians
15-198-87-116-69-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Nationals
17-189-78-113-314-15
Guardians
17-15-27-910-6-27-510-9-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Nationals
16-199-77-123-313-16
Guardians
20-1411-59-910-210-11

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 4th@CINW 4-1-1.5 WU 8.5WSH -112
May 3rd@CINW 11-6+1.5 WO 9WSH +164
May 2nd@CINL 1-6+1.5 LU 9CIN +168
May 1st@PHIW 4-2+1.5 WU 10WSH +150
Apr 30th@PHIL 2-7+1.5 LO 8PHI +210

Guardians vs. Nationals Injury Updates

Guardians Injuries

  • Shane Bieber
    P

    Bieber is out with elbow

    Out

  • Slade Cecconi
    P

    Cecconi is out with oblique

    Out

  • John Means
    P

    Means is out with elbow

    Out

  • Lane Thomas
    OF

    Thomas is out with wrist

    Out

  • David Fry
    C

    Fry is out with elbow

    Out

Nationals Injuries

  • Michael Soroka
    P

    Soroka is out with biceps

    Out

  • Paul DeJong
    IF

    DeJong is out with nose

    Out

  • Josiah Gray
    P

    Josiah Gray (elbow) scratched Tuesday.

    Out

  • Andres Chaparro
    IF

    Chaparro is out with oblique

    Out

  • Cade Cavalli
    P

    Cavalli is out with elbow

    Out

  • DJ Herz
    P

    Herz is out with elbow

    Out

Guardians vs. Nationals Starting Lineups
Guardians Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Luis L. Ortiz logoRL.Ortiz, P2-34.781.40610.13
HITTERSAVGOBPSLGHR
Steven Kwan logo1S.Kwan, LF.333.384.4674
Daniel Schneemann logo2D.Schneemann, 2B.274.348.5484
Jose Ramirez logo3J.Ramirez, 3B.265.318.4365
Kyle Manzardo logo4K.Manzardo, 1B.219.325.4958
Carlos Santana logo5C.Santana, DH.219.316.3163
Bo Naylor logo6B.Naylor, C.184.284.4085
Gabriel Arias logo7G.Arias, SS.262.319.4374
Nolan Jones logo8N.Jones, RF.156.278.2601
Angel Martinez logo9A.Martinez, CF.324.329.4120
Nationals Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Jake Irvin logoRJ.Irvin, P2-14.011.1256.96
HITTERSAVGOBPSLGHR
CJ Abrams logo1C.Abrams, SS.284.333.5234
Alex Call logo2A.Call, LF.344.449.4260
James Wood logo3J.Wood, DH.273.381.5459
Nathaniel Lowe logo4N.Lowe, 1B.254.331.4466
Keibert Ruiz logo5K.Ruiz, C.298.350.3862
Luis Garcia logo6L.Garcia, 2B.234.282.3603
Dylan Crews logo7D.Crews, RF.197.248.3254
Jose Tena logo8J.Tena, 3B.231.259.3080
Jacob Young logo9J.Young, CF.213.315.2500

Guardians vs. Nationals Odds Comparison

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Guardians at Nationals Team Totals

MatchupOverUnder
Guardians
20-14
N/A
N/A
Nationals
16-19
N/A
N/A