Astros vs. Pirates Odds & Betting Predictions - June 4, 2025

Astros at Pirates

10:40 pm • SCHN

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Houston Astros

33-27

Pittsburgh Pirates

22-39

pitcher		team	era	w-l
M.Burrows			0.00	0-0
R.Gusto			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Astros 33-27	-1.5	-1.5+125	o9-130	-125
Pirates 22-39	u9	+1.5-152	u9-120	+106

Wednesday 10:40 p.m.

June 04, 2025

PNC ParkPittsburgh

82°Fahrenheit

0%Rain

6Wind

PIT +115

Follow @PicksOffice on X. Gusto’s in freefall – 9.58 ERA, 2.32 WHIP last 3 starts. Got rocked for 13 ER in 3.2 IP vs Tampa. 19 walks in 39 IP shows major control issues. Pirates get a hittable rookie with no confidence. Houston hitting just .221 on the road, .179 vs LHP – massive drop-off away from home. Astros hitting .225 vs RHP on the road. Pittsburgh recently hung 10 runs on Arizona at home, showing clear upside. PNC’s pitching-friendly dimensions + wind could keep the game tight and favor contact bats. Astros’ bullpen bleeding - Historical edge too – PIT 12-7 last 19 home games vs HOU, including a 14-2 and 10-0 beatdown. Pressure on Houston, not PIT – home crowd, looser team, better matchup today.

O.Cruz o1.5 Total Bases+108

0.93u

O.Cruz o1.5 Total Bases+108

PIT +112

R.Gusto o2.5 Earned Runs+125

PIT +120

0.5u

Bet to +110

HOU -1.5+120

PRO's +830, +875 Home Run Bangers
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Jun 4, 2025 UTC
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Zerillo's Wednesday MLB Predictions & Betting Card
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No props found

MLB Public Betting

Pirates are 2-3 in their last 5 games.
Pirates are 3-2 in their last 5 games against the spread
Pirates are 13-18 in their road games against the spread
The totals have gone OVER in 2 of Pirates' last 5 games
The totals have gone OVER in 13 of Pirates' 30 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Pirates	27-34	14-16	13-18	4-14	23-20
Astros	32-28	18-16	14-12	17-23	15-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Pirates	23-34-4	13-15-2	10-19-2	7-11	16-23-4
Astros	24-34-2	14-20	10-14-2	20-20	3-14-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Pirates	22-39	13-17	9-22	6-12	16-27
Astros	33-27	22-12	11-15	22-18	11-8

date	opponent	score	spread	over/under	moneyline
Jun 3rd	HOU	L 0-3	-1.5 L	U 7	HOU -162
Jun 1st	@SD	L 4-6	+1.5 L	O 8.5	SD +127
Jun 1st	@SD	W 5-0	+1.5 W	U 7.5	PIT +191
May 31st	@SD	L 2-3	+1.5 W	U 7.5	SD +160
May 28th	@ARI	W 10-1	+1.5 W	O 7.5	PIT +114

Taylor Trammell
OF
Trammell is out with calf
Out
Cristian Javier
P
Javier is out with elbow
Out
Luis Garcia
P
Garcia is out with elbow
Out
Pedro Leon
OF
Leon is out with knee
Out
J.P. France
P
France is out with shoulder
Out
Hayden Wesneski
P
Wesneski is out with elbow
Out
Spencer Arrighetti
P
Arrighetti is out with thumb
Out

Johan Oviedo
P
Oviedo is questionable with elbow
Questionable
Jared Jones
P
Jones is out with elbow
Out
Jared Triolo
IF
Triolo is questionable with back
Questionable
Spencer Horwitz
IF
Horwitz is questionable with wrist
Questionable

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MatchupOverUnder
Astros 33-27	N/A	N/A
Pirates 22-39	N/A	N/A

Astros vs. Pirates Odds & Betting Predictions - June 4, 2025

Astros at Pirates

Houston Astros

Pittsburgh Pirates

Astros at Pirates Odds

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Astros vs. Pirates Previews & Analysis

PRO's +830, +875 Home Run Bangers

Astros vs. Pirates: A Weather Edge for Wednesday

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