Boston Col vs. Louisville Odds & Betting Predictions - October 25, 2025
Boston Col at Louisville
11:30 pm • ACC NetworkBoston Col at Louisville Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Boston Col 1-7 | +22.5 | +25.5-110 | o54.5-110 | +1300 |
Louisville 6-1 | u53.5 | -25.5-110 | u54.5-110 | -2800 |

L&N Federal Credit Union StadiumLouisville
Boston Col vs. Louisville Expert Picks
FTN Fantasy
Last 30d: 48-45-1 (+4.8u)
LOU -12.5 (Live)-115
0.87u
LOU -14.5 (Live)-115
1u
The Degenerates
Last 30d: 58-57-0 (-3.9u)
LOU -25.5-105
1.05u
💰🦡 Jake
Last 30d: 116-129-6 (+3.8u)
BC +14.5 (1H)-114
1.5u
Boston Col vs. Louisville Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Boston Col vs. Louisville Public Betting Percentages
Betting Trends
- Louisville are 4-1 in their last 5 games.
- Louisville are 1-4 in their last 5 games against the spread
- Louisville are 2-0 in their road games against the spread
- The totals have gone OVER in 3 of Louisville' last 5 games
- The totals have gone OVER in 3 of Louisville' 5 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 2-5 | 0-5 | 2-0 | 1-5 | 1-0 | |
| 3-5 | 1-3 | 2-2 | 1-2 | 2-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-3 | 3-2 | 1-1 | 4-2 | 0-1 | |
| 6-2 | 2-2 | 4-0 | 2-1 | 4-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-1 | N/A | N/A | 5-1 | 1-0 | |
| 1-7 | N/A | N/A | 1-2 | 0-5 |
Last 5 Matchups
Team Stats
360
Total Yards
504
82
Total Plays
59
4.390243902439025
Yards Per Play
8.542372881355933
244
YDS
187
23/46
Comps/Atts
15/28
5.304347826086956
YPA
6.678571428571429
3/2
TDs/INTs
1/1
2/13
Sacks/Yards
1/2
5/40
Penalties/Yards
6/45
Boston Col vs. Louisville Odds Comparison
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Boston Col at Louisville Team Totals
MatchupOverUnder | ||
|---|---|---|
Boston Col 1-7 | o13.5-130 | u13.5-101 |
Louisville 6-1 | o40.5-114 | u40.5-113 |






