Orioles vs. White Sox Odds & Betting Predictions - September 16, 2025

Orioles at White Sox

11:40 pm • CHSN
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Starting Pitchers
pitcherteameraw-l
Shane Smith logoS.SmithChicago White Sox logo3.786-7
Dean Kremer logoD.KremerBaltimore Orioles logo4.439-10

Orioles at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
70-80
+1.5
-1.5+158
o8-102
-108
White Sox
57-94
u8.5
+1.5-191
u8-116
-110
location pinTuesday 11:40 p.m.
September 16, 2025
Rate FieldChicago
thermometer image73°Fahrenheit
rain image0%Rain
wind image4Wind
Orioles vs. White Sox Expert Picks
Sean Zerillo
Sean Zerillo
Last 30d: 163-184-4 (-7.6u)
BAL +120
0.5u
Bet to +104

Orioles vs. White Sox Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Orioles vs. White Sox Public Betting Percentages

Away Logo

Orioles

Public

63%

Bets%

37%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
88-6344-3244-310-287-61
Orioles
73-7734-4039-3723-4048-37

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
70-74-740-31-530-43-20-269-72-7
Orioles
62-84-433-39-229-45-231-30-230-53-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
57-9432-4425-501-155-93
Orioles
70-8036-3834-4230-3338-47

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 15thBALL 1-4+1.5 LU 8BAL +117
Sep 14th@CLEL 2-3+1.5 WU 8CLE +130
Sep 13th@CLEL 1-3+1.5 LU 7.5CLE +146
Sep 12th@CLEL 0-4+1.5 LU 7.5CLE +119
Sep 11thTBW 5-1+1.5 WU 7.5CWS +110

White Sox vs. Orioles Injury Updates

White Sox Injuries

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Orioles Injuries

  • Grayson Rodriguez
    SP

    Rodriguez is out with elbow

    Out

Orioles vs. White Sox Starting Lineups
Orioles Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Dean Kremer logoRD.Kremer, P9-104.431.2577.51
HITTERSAVGOBPSLGHR
Jackson Holliday logo1J.Holliday, 2B.255.325.39617
Jeremiah Jackson logo2J.Jackson, 3B.284.318.4615
Gunnar Henderson logo3G.Henderson, SS.269.346.43916
Ryan Mountcastle logo4R.Mountcastle, 1B.256.293.3645
Dylan Beavers logo5D.Beavers, LF.267.421.3731
Tyler O'Neill logo6T.O'Neill, RF.208.290.4168
Samuel Basallo logo7S.Basallo, C.185.250.3332
Jordan Westburg logo8J.Westburg, DH.276.326.47315
Colton Cowser logo9C.Cowser, CF.202.271.39415
White Sox Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Shane Smith logoRS.Smith, P6-73.781.1838.38
HITTERSAVGOBPSLGHR
Mike Tauchman logo1M.Tauchman, RF.262.353.3958
Kyle Teel logo2K.Teel, DH.279.376.4207
Lenyn Sosa logo3L.Sosa, 1B.260.291.42620
Colson Montgomery logo4C.Montgomery, SS.222.294.51418
Miguel Vargas logo5M.Vargas, 3B.231.312.39714
Andrew Benintendi logo6A.Benintendi, LF.240.304.42419
Edgar Quero logo7E.Quero, C.279.342.3775
Chase Meidroth logo8C.Meidroth, 2B.270.347.3445
Dominic Fletcher logo9D.Fletcher, CF.231.231.4620

Orioles vs. White Sox Odds Comparison

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Orioles at White Sox Team Totals

MatchupOverUnder
Orioles
70-80
N/A
N/A
White Sox
57-94
N/A
N/A