White Sox vs. Guardians Odds & Betting Predictions - September 14, 2025

White Sox at Guardians

5:40 pm • CHSN

Chicago White Sox

2

2 - 3

Cleveland Guardians

3

pitcher		team	era	w-l
S.Cecconi			4.30	7-7
Y.Gomez			2.70	1-1

MatchupOpenSpreadTotalMoneyline
White Sox 0-0	+1.5	+1.5-164	o8+100	+130
Guardians 1-2	u8.5	-1.5+137	u8-118	-162

location pin

Sunday 5:40 p.m.

September 14, 2025

Progressive FieldCleveland

No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 1-4 in their last 5 games against the spread
Guardians are 47-34 in their road games against the spread
The totals have gone OVER in 2 of Guardians' last 5 games
The totals have gone OVER in 37 of Guardians' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	86-76	39-42	47-34	33-36	51-38
White Sox	94-68	47-34	47-34	0-2	92-66

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5
White Sox	75-80-7	42-34-5	33-46-2	0-2	73-78-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	88-74	45-36	43-38	44-25	43-46
White Sox	60-102	33-48	27-54	1-1	58-100

date	opponent	score	spread	over/under	moneyline
Sep 13th	CWS	W 3-1	-1.5 W	U 7.5	CLE -171
Sep 12th	CWS	W 4-0	-1.5 W	U 7.5	CLE -142
Sep 11th	KC	W 3-2	-	-	CLE -144
Sep 10th	KC	L 3-4	+1.5 W	U 8	KC -110
Sep 9th	KC	W 2-0	+1.5 W	U 7.5	CLE -110

Ben Lively
SP
Lively is out with elbow
Out
John Means
SP
Means is out with elbow
Out

Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RY.Gomez, P		77	5	4	2
LB.Eisert, P		25	1.2	1	1
LF.Ellard, P		11	0.1	0	0
RW.Gonzalez, P		19	1	1	0

HITTERS	H-AB	R	HR	RBI
1M.Tauchman, RF	0-4	0	0	0
2K.Teel, C	1-4	0	0	0
3L.Sosa, 1B	1-4	1	0	0
4C.Montgomery, SS	0-3	0	0	0
5M.Vargas, 3B	2-4	0	0	1
6A.Benintendi, DH	0-4	0	0	0
7W.Robertson, LF	0-3	0	0	0
8C.Meidroth, 2B	1-3	1	1	1
9D.Fletcher, CF	0-3	0	0	0

PITCHER		PC	IP	K	ER
RS.Cecconi, P		93	5.2	4	2
LT.Herrin, P		5	0.1	1	0
RM.Festa, P		14	1	3	0
RH.Gaddis, P		16	1	1	0
RC.Smith, P		12	1	2	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-3	1	0	0
2N.Jones, CF	0-2	0	0	0
2A.Martinez, PH	1-2	0	0	0
2A.Martinez, CF	1-2	0	0	0
3J.Ramirez, DH	1-3	1	0	0
4K.Manzardo, 1B	0-4	0	0	0
4J.Noel, RF	0-0	0	0	0
5B.Naylor, C	2-3	1	1	3
6G.Arias, SS	0-4	0	0	0
7D.Schneemann, 3B	1-3	0	0	0
8C.Kayfus, RF	1-3	0	0	0
8C.Kayfus, 1B	1-3	0	0	0
9B.Rocchio, 2B	0-2	0	0	0

Could not load odds

See more MLB Odds

MatchupOverUnder
White Sox 0-0	o3.5-105	u3.5-122
Guardians 1-2	o4.5+113	u4.5-144