Padres vs. Cardinals Odds & Betting Predictions - July 25, 2025

Padres at Cardinals

11:15 pm • FDSMW

San Diego Padres

60-49

0 - 3

St. Louis Cardinals

55-55

pitcher		team	era	w-l
M.Mikolas			4.83	6-8
N.Pivetta			2.81	10-3

MatchupOpenSpreadTotalMoneyline
Padres 60-49	-1.5	-1.5+134	o8.5-112	-130
Cardinals 55-55	u8.5	+1.5-158	u8.5-106	+110

Friday 11:15 p.m.

July 25, 2025

Busch StadiumSt. Louis

SD -145 (F5)

0.73u

F5 Non Div Fav on Losing Streak (***) Overall: 180-89-45,67% (ROI:14%) Season:13-4-3,76% (ROI:25%)

STL +120

1.2u

Under 8.5-105

🔪

SD -136 (F5)

1.36u

Did not mean to play this for full unit - .5u spot

SD -130

Nick Pivetta, that's it, place the bet. Pivetta is 10-2 with a 2.81 ERA this season and has been the Padres best pitcher. He now will face a Cardinals team that has been all over the place of late. I would have loved to play a Pivetta ER prop here, but the books are heavily juicing his lines, so the moneyline is a nice 2nd option. Mikolas will be on the mound for the Cardinals, and I think this Padres lineup can get to him. Mikolas holds a 5-7 record and a 5.20 ERA this season. This Padres lineup is slowly waking up with guys like Jackson Merrill starting to heat back up, and Mikolas has a favorable pitch mix to provide some run support for Pivetta.

F.Tatis o0.5 HR+400

0.5u

STL +1-118

SD -1.5+135

STL +120

3.6u

SD -130 (F5)

1.3u

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No props found

MLB Public Betting

Cardinals are 1-4 in their last 5 games.
Cardinals are 1-4 in their last 5 games against the spread
Cardinals are 27-27 in their road games against the spread
The totals have gone OVER in 1 of Cardinals' last 5 games
The totals have gone OVER in 29 of Cardinals' 56 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	57-53	30-26	27-27	22-31	34-22
Padres	59-50	29-23	30-27	25-31	33-19

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	55-49-6	29-24-3	26-25-3	26-22-5	28-27-1
Padres	43-62-4	20-31-1	23-31-3	27-27-2	16-34-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	55-55	32-24	23-31	27-26	27-29
Padres	60-49	34-18	26-31	33-23	26-26

date	opponent	score	spread	over/under	moneyline
Jul 24th	SD	W 9-7	-1.5 W	O 7.5	STL -155
Jul 23rd	@COL	L 0-6	-1.5 L	U 11	COL -190
Jul 23rd	@COL	L 4-8	-1.5 L	U 12	COL -170
Jul 22nd	@COL	W 6-2	-1.5 W	U 12	STL -181
Jul 20th	@ARI	L 3-5	+1.5 L	U 9	ARI +121

Nolan Arenado
3B
Arenado is out with shoulder
Out
Nolan Gorman
2B
Gorman is out with back
Out

Joe Musgrove
SP
Musgrove is out for season with elbow
Out for Season
Michael King
SP
Michael King (shoulder) has been scratched Saturday. Sean Reynolds will start for the Padres.
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RN.Pivetta, P	90	6.1	4	2
LW.Peralta, P	6	0.2	0	0
RD.Morgan, P	9	1	0	0

HITTERS	H-AB	R	HR	RBI
1F.Tatis, RF	2-4	0	0	0
2L.Arraez, 1B	1-4	0	0	0
3M.Machado, DH	2-4	0	0	0
4J.Merrill, CF	1-4	0	0	0
5X.Bogaerts, SS	2-4	0	0	0
6G.Sheets, LF	0-4	0	0	0
7J.Cronenworth, 2B	1-4	0	0	0
8J.Iglesias, 3B	1-4	0	0	0
9E.Diaz, C	1-2	0	0	0
9T.Brooks, PH	0-1	0	0	0
9M.Maldonado, C	0-1	0	0	0

PITCHER	PC	IP	K
RM.Mikolas, P	73	5	1
LS.Matz, P	11	1	0
RP.Maton, P	9	1	1
LJ.Romero, P	9	1	0
RR.Helsley, P	13	1	2

HITTERS	H-AB	R	RBI
1B.Donovan, 2B	0-4	0	0
2I.Herrera, DH	2-4	0	0
3A.Burleson, LF	0-4	0	0
3G.Hampson, PR	0-0	0	0
3G.Hampson, LF	0-0	0	0
4W.Contreras, 1B	2-2	2	0
5N.Arenado, 3B	0-3	1	0
6M.Winn, SS	1-2	0	2
7Y.Pozo, C	0-3	0	1
8J.Walker, RF	0-3	0	0
9V.Scott, CF	0-3	0	0