Giants vs. Padres Odds & Betting Predictions - August 21, 2025
Giants at Padres
8:10 pm • SDPAStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
 |  | 4.61 | 5-11 | |
 |  | 4.23 | 1-9 |
Giants at Padres Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Giants 61-66 | +1.5 | +1.5-137 | o7.5-120 | +158 |
Padres 71-56 | u8 | -1.5+114 | u7.5-102 | -191 |
PETCO ParkSan Diego
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Giants vs. Padres Expert Picks
YBK Picks.com
Last 30d: 11-19-2 (-17.3u)
SD -1.5+115
2u
💰🦡 Jake
Last 30d: 69-73-2 (-3.1u)
Under 0.5 (1st Inn)-120
1.2u
Allan Lem
Last 30d: 63-61-3 (-2.2u)
Under 8-118
0.59u
Under is popping in the Action models so I’ll bite
Sean Zerillo
Last 30d: 152-171-4 (-0.8u)
Under 8-110
0.55u
Bet to -115
SD -150 (F5)
0.38u
Small to -165
Giants vs. Padres Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Giants vs. Padres Public Betting Percentages
Betting Trends
- Padres are 2-3 in their last 5 games.
- Padres are 3-2 in their last 5 games against the spread
- Padres are 36-30 in their road games against the spread
- The totals have gone OVER in 2 of Padres' last 5 games
- The totals have gone OVER in 26 of Padres' 61 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Giants vs. Padres Injury Updates
Giants Injuries
- Tom MurphyC
Murphy is out with back
Out
Padres Injuries
- Joe MusgroveSP
Musgrove is out for season with elbow
Out for Season
- Michael KingSP
Michael King (shoulder) has been scratched Saturday. Sean Reynolds will start for the Padres.
Out
Giants vs. Padres Starting Lineups
Giants Starting Lineup| PITCHER | W-L | ERA | WHIP | K/9 | |
|---|---|---|---|---|---|
 | 1-9 | 4.23 | 1.420 | 8.04 |
| HITTERS | AVG | OBP | SLG | HR |
|---|---|---|---|---|
 | .262 | .324 | .415 | 7 |
 | .265 | .338 | .407 | 15 |
 | .272 | .401 | .504 | 15 |
 | .221 | .307 | .390 | 19 |
 | .282 | .343 | .403 | 3 |
 | .246 | .319 | .411 | 8 |
 | .263 | .306 | .376 | 3 |
 | .167 | .208 | .351 | 5 |
 | .164 | .207 | .218 | 1 |
Padres Starting Lineup| PITCHER | W-L | ERA | WHIP | K/9 | |
|---|---|---|---|---|---|
 | 5-11 | 4.61 | 1.312 | 11.60 |
| HITTERS | AVG | OBP | SLG | HR |
|---|---|---|---|---|
 | .266 | .372 | .433 | 17 |
 | .287 | .323 | .395 | 6 |
 | .292 | .353 | .484 | 21 |
 | .283 | .374 | .463 | 13 |
 | .264 | .333 | .392 | 10 |
 | .257 | .320 | .447 | 17 |
 | .290 | .355 | .529 | 15 |
 | .240 | .358 | .380 | 9 |
 | .255 | .309 | .339 | 3 |
Giants vs. Padres Odds Comparison
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Giants at Padres Team Totals
MatchupOverUnder | ||
|---|---|---|
Giants 61-66 | N/A | N/A |
Padres 71-56 | N/A | N/A |