Sweet 16 Betting Odds: Point Spreads, Over/Unders for All 8 NCAA Tournament Games

Sweet 16 Betting Odds: Point Spreads, Over/Unders for All 8 NCAA Tournament Games article feature image
Credit:

David Butler II-USA TODAY Sports. Pictured: Carsen Edwards

  • Opening point spreads for the NCAA Tournament's Sweet 16 have been released.
  • Get those below, plus Sean Koerner's projected spreads and over/unders to help find betting value.
  • All 16 favorites won straight-up in the second round, which has created more competitive matchups in the Sweet 16.

The first weekend of the NCAA Tournament is in the books, which means it’s about time to start looking ahead to second weekend and the Sweet 16.

All lines have opened, and each has a point spread in single digits. Favorites going 16-0 straight-up in the second round has created more competitive matchups.

Find opening odds below, and see Sean Koerner’s projected spreads FREE in The Action Network app.

NCAA Tournament Sweet 16 Betting Odds

#1 Duke vs. #4 Virginia Tech NCAA Tournament Betting Odds

  • Spread: Duke -7.5
  • Over/Under: 146.5
  • Date: Friday, March 29
  • Time: 9:39 p.m. ET
  • Location: Washington D.C.
  • TV: CBS

#1 Gonzaga vs. #4 Florida State NCAA Tournament Betting Odds

  • Spread: Gonzaga -7
  • Over/Under: 148
  • Date: Thursday, March 28
  • Time: 7:09 p.m. ET
  • Location: Anaheim, Calif.
  • TV: CBS

#2 Michigan State vs. #3 LSU NCAA Tournament Betting Odds

  • Spread: Michigan State -6
  • Over/Under: 149
  • Date: Friday, March 29
  • Time: 7:09 p.m. ET
  • Location: Washington D.C.
  • TV: CBS

#2 Tennessee vs. #3 Purdue NCAA Tournament Betting Odds

  • Spread: Tennessee -1
  • Over/Under: 146.5
  • Date: Thursday, March 28
  • Time: 7:29 p.m. ET
  • Location: Louisville, Ky.
  • TV: TBS

#1 North Carolina vs. #5 Auburn NCAA Tournament Betting Odds

  • Spread: UNC -5
  • Over/Under: 159.5
  • Date: Friday, March 29
  • Time: 7:29 p.m. ET
  • Location: Kansas City, Mo.
  • TV: TBS

#2 Michigan vs. #3 Texas Tech NCAA Tournament Betting Odds

  • Spread: Michigan -2
  • Over/Under: 126
  • Date: Friday, March 29
  • Time: 9:59 p.m. ET
  • Location: Anaheim, Calif.
  • TV: TBS

#2 Kentucky vs. #3 Houston NCAA Tournament Betting Odds

  • Spread: Kentucky -3
  • Over/Under: 136
  • Date: Friday, March 29
  • Time: 9:59 p.m. ET
  • Location: Kansas City, Mo.
  • TV: TBS

#1 Virginia vs. #12 Oregon NCAA Tournament Betting Odds

  • Spread: Virginia -7.5
  • Over/Under: 118.5
  • Date: Thursday, March 28
  • Time: 9:59 p.m. ET
  • Location: Louisville, Ky.
  • TV: TBS

Sean Koerner’s Projected Spreads

Get point spreads for this game and every possible tournament matchup with our bracket simulator built by Sean Koerner, our Director of Predictive Analytics, a former oddsmaker and FantasyPros’ most accurate in-season fantasy football ranker from 2015-2017.

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