Iowa vs. Iowa State Odds & Betting Predictions - September 6, 2025

Iowa at Iowa State

4:00 pm • FOX
13 - 16

Iowa at Iowa State Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Iowa
1-1
+2
+3.5-118
o42.5-115
+140
Iowa State
3-0
u45.5
-3.5-110
u42.5-115
-170
location pinSaturday 4:00 p.m.
September 06, 2025
Jack Trice StadiumAmes
Iowa vs. Iowa State Expert Picks
Collin Wilson
Collin Wilson
Last 30d: 45-28-5 (+13.0u)
Over 37.5 (Live)-110
0.55u
Boomer Betz
Boomer Betz
Last 30d: 166-190-0 (-47.0u)
IOWA +3.5 (Live)+105
0.53u
The Degenerates
The Degenerates
Last 30d: 62-68-1 (-14.4u)
Under 41.5-108
1u
Mjaybrod
Mjaybrod
Last 30d: 15-31-0 (-18.0u)
ISU u23.5 Team Total-110
0.91u
This is how I tail Biev
Capper Central
Capper Central
Last 30d: 95-70-1 (+12.2u)
IOWA +3.5-110
1u
Sir Lockselot
Sir Lockselot
Last 30d: 23-60-0 (-47.0u)
IOWA +145
3u
📚Player Profit 🔑 Iowa ML +145 (Player Profit) 3u Getting it going early with a 3u hammer. Iowa’s run-heavy offense plays well against a weak run D in Iowa St. huge rivalry game, spread only 3.5, value in the ML dog. Think Iowa gets it done today on the road Code: sirlocks for 10% off every purchase at playerprofit.com
Sean Zerillo
Sean Zerillo
Last 30d: 199-194-5 (+7.1u)
IOWA +3.5-110
0.25u
Jeremiah Rose
Jeremiah Rose
Last 30d: 19-17-2 (+1.9u)
ISU -2.5-130
0.77u
Big Bets On Campus (CFB)
Big Bets On Campus (CFB)
Last 30d: 28-26-1 (-0.9u)
IOWA +3.5-110
0.91u
Brian Bitler
Brian Bitler
Last 30d: 95-83-0 (+28.3u)
IOWA +3.5-110
2.73u
Collin Wilson
Collin Wilson
Last 30d: 45-28-5 (+13.0u)
IOWA +3.5-115
1u
As discussed on BBOC Podcast
Allan Lem
Allan Lem
Last 30d: 84-80-7 (-2.2u)
B.Eskildsen u37.5 Rec Yds-109
0.55u
Tailing @MrTuttle05
Mike Calabrese
Mike Calabrese
Last 30d: 15-16-0 (+3.3u)
IOWA +130
1u
They didn’t put much on film through the air against Albany and that was on purpose. Iowa State is going to be surprised by Iowa’s passing sophistication. #CyHawk ⚫️🟡🦅
Sandy Plashkes
Sandy Plashkes
Last 30d: 50-62-2 (-13.0u)
IOWA +3-110
1.1u
Boomer Betz
Boomer Betz
Last 30d: 166-190-0 (-47.0u)
IOWA +3.5-118
0.85u
@braydenhenry
Ryan Sura
Ryan Sura
Last 30d: 46-51-5 (-6.2u)
IOWA +3-110
1.1u

Iowa vs. Iowa State Previews & Analysis

  • Our NCAAF Best Bets for Saturday's Noon Games article feature image

    Our NCAAF Best Bets for Saturday's Noon Games

    Action Network Staff
    Sep 6, 2025 UTC
  • Iowa vs. Iowa State: How to Bet Cy-Hawk Game article feature image

    Iowa vs. Iowa State: How to Bet Cy-Hawk Game

    Collin Wilson
    Sep 6, 2025 UTC
  • Ziefel's CFB Props For Week 2 article feature image

    Ziefel's CFB Props For Week 2

    Doug Ziefel
    Sep 6, 2025 UTC
  • Our +190 SGP for Iowa vs. Iowa State article feature image

    Our +190 SGP for Iowa vs. Iowa State

    Dead President Picks
    Sep 6, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Iowa vs. Iowa State Public Betting Percentages

Away Logo

Iowa

Public

49%

Bets%

51%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Iowa State
2-11-1N/A1-11-0
Iowa
1-10-11-00-11-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Iowa State
1-21-1N/A1-10-1
Iowa
0-20-10-10-10-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Iowa State
3-0N/AN/A2-01-0
Iowa
1-1N/AN/A1-00-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 30thSDAKW 55-7-16.5 WO 47.5ISU -850
Aug 23rd@KSUW 24-21+3 WU 51.5ISU +125
Dec 28th@MIAW 42-41+5 WO 62.5ISU +176
Dec 7th@ASUL 19-45-1.5 LO 51ASU -120
Dec 1stKSUW 29-21-2.5 WU 51.5ISU -122
Team Stats
214
Total Yards
238
63
Total Plays
57
3.3968253968253967
Yards Per Play
4.175438596491228
83
YDS
134
13/24
Comps/Atts
18/27
3.4583333333333335
YPA
4.962962962962963
0/1
TDs/INTs
1/0
3/17
Sacks/Yards
0/0
131
Rush Yards
104
39
Attempts
30
3.358974358974359
YPC
3.466666666666667
1
TDs
0
0
Fumbles Lost
1
1
Interceptions
0

Efficiency

3/3 100%
Redzone
2/3 66.67%
5/14 0%
3rd Down
8/15 0%
1/2 0%
4th Down
0/0 0%

First Downs

15
Total
14
5
Pass
5
8
Rush
8
2
Penalty
1
4/38
Penalties/Yards
5/42

Iowa vs. Iowa State Odds Comparison

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Iowa at Iowa State Team Totals

MatchupOverUnder
Iowa
1-1
o19.5-126
u19.5-105
Iowa State
3-0
o23.5-109
u23.5-121