Chargers vs Giants Odds & Live Scores - September 28, 2025

MatchupOpenSpreadTotalMoneyline
Chargers 3-1	-3.5	-6-105	o42.5-110	-280
Giants 1-3	u43.5	+6-115	u42.5-110	+225

NYG -115 (Live)

1u

LAC -6 (Live)-110

1.1u

Under 43-110

0.45u

O.Hampton u70.5 Rush Yds-110

0.83u

NYG +6.5-114

0.25u

Small Luck Rankings play Will have as part of Luck Rankings round robin

NYG +6.5-115

0.35u

Think Dart will be an upgrade but obviously huge range

NYG +6.5-114

0.88u

LAC -6.5-105

2u

O.Gadsden o2.5 Recs+130

1u

J.Herbert o15.5 Rush Yds-115

0.87u

L.McConkey o5.5 Recs+113

1u

J.Dart o189.5 Pass Yds-120

1u

NYG +6-102

2.94u

O.Gadsden Anytime TD Scorer Yes+350

0.2u

O.Gadsden o2.5 Recs+120

1u

NYG +6.5-110

1u

NYG +6.5-110

0.91u

#SundaySixPack

O.Hampton o119.5 Rush Yds+1000

1.5u

Remember how the Giants were a sneaky top-10-potential defense? Turns out not so much. New York ranks 30th in Defensive DVOA so far and dead last against the run. The Giants are so bad against the rush that even the Chiefs were able to run on them! This isn't new either. The Giants allowed almost 1900 rushing yards to RBs last season, fifth most in the NFL, with the median outcome for a lead RB at 87 yards, so over half the games! This season the Giants are allowing 5.2 yards per carry, and that's against Washington, Dallas, and Kansas City — not exactly a murderer's row of opposing running backs. Volume is key here. Since the start of last season, RBs with 14+ carries against the Giants are averaging 121 rushing yards. With Najee Harris out for the season, Hampton should see a huge workload under notoriously run-heavy OC Greg Roman. Hampton had 19 carries just last week even with Harris playing part of the game, and he had 23 carries the first two games even in a part-time role. Play Hampton to go over 62.5 rushing yards (BetRivers), considering he hit that already last week with 70 yards against a far better defense despite playing part-time. This is a great opportunity for a Hampton breakout game too. Six RBs hit 100 yards against the Giants last season, so let's play Hampton to do that at +475 (bet365). He's +1000 to make it to 120 rushing yards, right at that average outcome for RBs with 14+ carries against New York. If Hampton does have a huge rushing game, we'll definitely want that Offensive Rookie of the Year ticket too at +900 (Circa). I'm selling high on Emeka Egbuka with other Bucs WRs coming back and on Tyler Warren since a tight end has never won the award, and I'm not buying Dart with a rough upcoming schedule. This race feels open to some of the RBs slowly nudging themselves into a bigger role, and Hampton leads the pack. If he has a big game against the Giants on Sunday, Omarion Hampton could wake up Monday morning as a Rookie of the Year favorite.

O.Hampton o62.5 Rush Yds-112

0.89u

Remember how the Giants were a sneaky top-10-potential defense? Turns out not so much. New York ranks 30th in Defensive DVOA so far and dead last against the run. The Giants are so bad against the rush that even the Chiefs were able to run on them! This isn't new either. The Giants allowed almost 1900 rushing yards to RBs last season, fifth most in the NFL, with the median outcome for a lead RB at 87 yards, so over half the games! This season the Giants are allowing 5.2 yards per carry, and that's against Washington, Dallas, and Kansas City — not exactly a murderer's row of opposing running backs. Volume is key here. Since the start of last season, RBs with 14+ carries against the Giants are averaging 121 rushing yards. With Najee Harris out for the season, Hampton should see a huge workload under notoriously run-heavy OC Greg Roman. Hampton had 19 carries just last week even with Harris playing part of the game, and he had 23 carries the first two games even in a part-time role. Play Hampton to go over 62.5 rushing yards (BetRivers), considering he hit that already last week with 70 yards against a far better defense despite playing part-time. This is a great opportunity for a Hampton breakout game too. Six RBs hit 100 yards against the Giants last season, so let's play Hampton to do that at +475 (bet365). He's +1000 to make it to 120 rushing yards, right at that average outcome for RBs with 14+ carries against New York. If Hampton does have a huge rushing game, we'll definitely want that Offensive Rookie of the Year ticket too at +900 (Circa). I'm selling high on Emeka Egbuka with other Bucs WRs coming back and on Tyler Warren since a tight end has never won the award, and I'm not buying Dart with a rough upcoming schedule. This race feels open to some of the RBs slowly nudging themselves into a bigger role, and Hampton leads the pack. If he has a big game against the Giants on Sunday, Omarion Hampton could wake up Monday morning as a Rookie of the Year favorite.

O.Hampton 100+ Rushing Yards Yes+475

1.66u

Remember how the Giants were a sneaky top-10-potential defense? Turns out not so much. New York ranks 30th in Defensive DVOA so far and dead last against the run. The Giants are so bad against the rush that even the Chiefs were able to run on them! This isn't new either. The Giants allowed almost 1900 rushing yards to RBs last season, fifth most in the NFL, with the median outcome for a lead RB at 87 yards, so over half the games! This season the Giants are allowing 5.2 yards per carry, and that's against Washington, Dallas, and Kansas City — not exactly a murderer's row of opposing running backs. Volume is key here. Since the start of last season, RBs with 14+ carries against the Giants are averaging 121 rushing yards. With Najee Harris out for the season, Hampton should see a huge workload under notoriously run-heavy OC Greg Roman. Hampton had 19 carries just last week even with Harris playing part of the game, and he had 23 carries the first two games even in a part-time role. Play Hampton to go over 62.5 rushing yards (BetRivers), considering he hit that already last week with 70 yards against a far better defense despite playing part-time. This is a great opportunity for a Hampton breakout game too. Six RBs hit 100 yards against the Giants last season, so let's play Hampton to do that at +475 (bet365). He's +1000 to make it to 120 rushing yards, right at that average outcome for RBs with 14+ carries against New York. If Hampton does have a huge rushing game, we'll definitely want that Offensive Rookie of the Year ticket too at +900 (Circa). I'm selling high on Emeka Egbuka with other Bucs WRs coming back and on Tyler Warren since a tight end has never won the award, and I'm not buying Dart with a rough upcoming schedule. This race feels open to some of the RBs slowly nudging themselves into a bigger role, and Hampton leads the pack. If he has a big game against the Giants on Sunday, Omarion Hampton could wake up Monday morning as a Rookie of the Year favorite.

O.Gadsden 40+ Receiving Yards Yes+390

0.5u

O.Gadsden 60+ Receiving Yards Yes+1000

0.25u

C.Dicker o1.5 FGs Made-135

1u

L.McConkey o60.5 Rec Yds-110

1u

O.Gadsden o19.5 Rec Yds-118

1.2u

O.Hampton 120+ Rushing Yards Yes+1000

1u

@wheatonbrando https://myaction.app/QiU46AL9YWb

O.Hampton 100+ Rushing Yards Yes+475

0.95u

@wheatonbrando https://myaction.app/QiU46AL9YWb

O.Hampton o62.5 Rush Yds-110

0.91u

@wheatonbrando https://myaction.app/QiU46AL9YWb

NYG +6-110

1u

@BKPicks https://myaction.app/FqsJZ7B4YWb

K.Allen u51.5 Rec Yds-115

0.87u

NYG +6.5-110

0.91u

NYG +6.5-110

0.91u

@sundaysixpack @ChrisRaybon 1 https://myaction.app/JNv2zeOUXWb

NYG +6.5-110

1u

@ChrisRaybon 1 https://myaction.app/kzy8ZyeUXWb

C.Skattebo o19.5 Rec Yds-120

1.2u

Skattebo is set for a healthy role with Tyrone Tracy expected to miss time. The rookie led the Giants with a 25.8% target share in Week 3. Only the 49ers and Dolphins have targeted RBs more often than the Giants. Those teams have pretty well-known receiving backs. The Chargers have allowed the 6th-most targets and the 9th-most receptions to running backs. They’ve been pretty stingy in terms of yardage, but they haven’t faced a running back of Skattebo’s caliber (shoutout Jeanty).

Over 43.5-107

1u

Rookie QB making his first start vs an elite defense

NYG +257

0.64u

NYG +6.5-110

1u

This is a pretty gross play: a rookie making his first start against an undefeated LAC team (SU & ATS) and against a coach that has feasted in these situations. Harbaugh is 4-0 ATS vs rookie QB’s since he became the Chargers HC. But…betting the Chargers feels way too easy. The Giants have the travel advantage and I think Daboll is smart enough to dial back the playbook, simplify things for Dart and let Skattebo move the chains ⛓️‍💥. Let’s get an ugly cover, with the potential for an outright win (sprinkle the ML as well .25 units).

NYG +6.5-110

1u

J.Dart Anytime TD Scorer Yes+310

0.31u

C.Skattebo o53.5 Rush Yds-109

1u

J.Herbert o22.5 Pass Comp-110

0.91u

LAC -5.5-115

1u

@wheatonbrando Week 4 Hot Read https://myaction.app/SynoOQl1RWb

LAC -5.5-110

1u

LAC -5.5-115

1.5u

🔥 Week 4 Hot Read 🔥 Grab below 6 while you can.

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NFL Public Betting

Giants are 1-3 in their last 5 games.
Giants are 2-2 in their last 5 games against the spread
Giants are 1-1 in their road games against the spread
The totals have gone OVER in 1 of Giants' last 4 games
The totals have gone OVER in 0 of Giants' 2 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	2-2	1-1	1-1	N/A	2-2
Chargers	3-1	1-0	1-1	2-1	1-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	1-3	0-2	1-1	N/A	1-3
Chargers	1-3	0-1	0-2	0-3	1-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	1-3	N/A	N/A	N/A	1-3
Chargers	3-1	N/A	N/A	2-1	1-0

date	opponent	score	spread	over/under	moneyline
Sep 22nd	KC	L 9-22	+6 L	U 44.5	KC +245
Sep 14th	@DAL	L 37-40	+4.5 W	O 44.5	DAL +194
Sep 7th	@WAS	L 6-21	+6.5 L	U 45.5	WAS +230
Aug 22nd	NE	W 42-10	-4.5 W	O 36.5	NYG -225
Aug 16th	NYJ	W 31-12	-3 W	O 37.5	NYG -162

Malik Nabers
WR
Nabers is out with knee
Out
Tyrone Tracy
RB
Tracy is out with shoulder
Out

Will Dissly
TE
Dissly is out with knee
Out
Najee Harris
RB
Harris is out with achilles
Out

See more NFL Injuries

Chargers

Total

Giants

338

Total Yards

250

56

Total Plays

69

6

Yards Per Play

3.6

Chargers

Passing

Giants

203

YDS

119

23/41

Comps/Atts

14/21

4.326

YPA

3.296

1/2

TDs/INTs

1/0

2/17

Sacks/Yards

6/30

Chargers

Rushing

Giants

152

Rush Yards

161

13

Attempts

42

11.692

YPC

3.833

1

TDs

1

Chargers

Turnovers

Giants

0

Fumbles Lost

0

2

Interceptions

0

Chargers

Efficiency

Giants

0/1 0%

Redzone

2/5 40%

4/12 0%

3rd Down

7/15 0%

0/0 0%

4th Down

0/1 0%

Chargers

First Downs

Giants

17

Total

20

8

Pass

6

Rush

11

3

Penalty

3

Chargers

Misc

Giants

14/107

Penalties/Yards

8/43

24:32

Possession

35:28

MatchupOverUnder
Chargers 3-1	o24-110	u24-113
Giants 1-3	o18-111	u18-111

Chargers vs. Giants Odds & Betting Predictions - September 28, 2025

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