Cardinals-Chiefs Betting Preview: Will Mahomes Cover Another Double-Digit Spread?

Betting odds: Arizona Cardinals at Kansas City Chiefs

• Spread: Chiefs -16.5
• Over/Under: 49.5
• Time: 1 p.m. ET
• TV channel: CBS

Betting market: This is a big number, but two-thirds of bettors have not been scared away from taking the Chiefs. Despite the public support, they’ve fallen from the nice round number of -17 to -16.5.

There haven’t been any bet signals on the Cardinals, but they are receiving 45% of the money, which is 10% higher than their percentage of bets (check out the latest data here). — Mark Gallant

Trends to know: This is just the second time in the past 20 years that the Chiefs have been favored by 14 or more points, according to our Bet Labs data.

The previous time was Week 15 vs. Detroit in 2003, Trent Green and Priest Holmes combined for six touchdowns in a win and cover. — John Ewing

Did you know? Andy Reid’s teams have been favored by 14 or more points four other times in his career going 2-2 straight up and against the spread. His teams have lost and failed to cover in the past two games.

Reid hasn’t been profitable as a large favorite, going 22-24 ATS when giving more than seven points to an opponent in the regular season. — Ewing

The Chiefs can be the first team in the NFL this season to eclipse their preseason win total (8.5, over +115) with a win against the Cardinals. — Evan Abrams