Panthers vs. Colts Betting Odds, Predictions & Picks (December 22, 2019)

Panthers vs. Colts Betting Odds, Predictions & Picks (December 22, 2019) article feature image

Panthers vs. Colts Betting Odds

  • Panthers Spread: +7
  • Colts Spread: -7
  • Panthers Moneyline: +255
  • Colts Moneyline: -320
  • Over/Under: 46.5
  • Time: 1:00 p.m. ET, FOX
For real-time odds, go to the Panthers-Colts game page to find the best price to bet.


The Indianapolis Colts are a favorite against the Carolina Panthers in Week 16 of the 2019 NFL season.

Here are the betting trends, statistics, model predictions and picks you need to help wager on it.

Panthers vs. Colts Model Prediction

The Colts have a 68% chance of winning this game, according to our NFL model. The true point spread is the Colts -6.5, giving slight value to Carolina.

The over/under in our model is projected at 45.3, giving slight value to the under.

Statistical Matchup

The Panthers are averaging 0.02 more yards per play than the Colts this season.

  • Carolina Panthers are 4-5-1 ATS in the last 10 games
  • Indianapolis Colts are 4-5-1 ATS in the last 10 games

Betting Percentage Breakdown

As of December 21st, 57% of bets are on the Panthers +7.

The game total is 46.5 and 67% of bets are on the over.

Get real-time betting percentages for every NFL game here.

Panthers vs. Colts Betting Picks

  • 256 or Bust: Panthers +6.5

No prop bets currently available

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