Colts vs. Chargers Odds, Picks, Cheat Sheet, More

Colts vs. Chargers Odds, Picks, Cheat Sheet, More article feature image

Kirby Lee-USA TODAY Sports. Pictured: Philip Rivers

Colts at Chargers Betting Odds

  • Odds: Chargers -6.5
  • Total: 44.5
  • Time: 4:05 p.m. ET
  • TV Channel: CBS

All odds above are as of Friday and via PointsBet.

This matchup looks a lot different than it did just a few weeks ago.

Andrew Luck retired. Melvin Gordon is holding out. And stud safety Derwin James (foot) has been placed on Injured Reserve.

The Chargers have moved from 3- to 6.5-point favorites following Luck’s retirement. But is there hope for Jacoby Brissett and the Colts on the road?

You’ll find all our coverage of this game below, from our comprehensive betting guide to Sean Koerner’s projected odds and more.

Colts at Chargers Betting Guide, Picks

Our analysts and experts break down the most important angles of this game.

Here’s an excerpt, but you can read the full thing here.

Rule No. 1 in betting: Bookmakers live and die by public perception. And Luck is how most of the public perceives the Colts.

Not only was he the face of the franchise, not only did he retire unexpectedly, but the news broke during the first primetime college football game of the year, which led to a hastily arranged press conference afterward. As much as the fact Luck was retiring, the shock of the moment sent betting markets spiraling.

Before the news, the Colts had been 3-point underdogs to the Chargers. Afterward, the Luck-less Colts had moved to 7.5-point underdogs.

See our full betting breakdown for Colts-Chargers here.

Sean Koerner’s Projected Colts-Chargers Odds

Sean Koerner uses his NFL Power Ratings to project a spread and total for Sunday’s matchup. See whether he thinks Indianapolis is being undervalued.

Colts-Chargers Prop Bets

NFL player props offer tremendous value every week. Mike Randle analyzes Philip Rivers’ passing touchdowns prop.

Pick ‘Em Confidence Rating

Sean Koerner ranks every straight-up and against-the-spread pick for pools in his Pick ‘Em Confidence Ratings.

See where the Colts and Chargers rank.

Survivor Pool Recommendations

Should you roll with either Indianapolis or Los Angeles to open the season? Our NFL simulations reveal the best Week 1 survivor pool picks.

Rovell’s Vegas Report

Sharps are buying the Colts against the Chargers. Darren Rovell spoke to bookmakers about the betting action on this AFC showdown.

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