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Bills vs. Texans Odds & Pick: How We’re Betting Saturday’s AFC Wild Card Matchup

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USA Today Sports. Pictured: Deshaun Watson, Josh Allen

  • Our staff previews the most important matchups for Saturday's AFC Wild Card matchup between the Bills and Texans.
  • Find odds, how our experts are betting the spread, their favorite player props and more predictions below.

Bills at Texans Picks & Betting Odds: Wild Card Weekend

  • Odds: Texans -2.5
  • Over/Under: 43.5
  • Kickoff: 4:35 p.m. ET
  • TV Channel: ABC/ESPN

Odds as of Friday and via FanDuel, where Action Network users get a risk-free bet up to $500.


Wild Card Weekend kicks off with an AFC showdown between the 5-seeded Buffalo Bills and 4-seeded Houston Texans.

Deshaun Watson and Co. have been bet down from 3- to 2.5-point favorites since the line opened despite a slight majority of tickets backing them to cover.

So how are our experts projecting this game? They preview all the important matchups and make their picks.

Bills-Texans Injury Report

Which team is healthier? Bills

All four players on the Bills’ injury report are listed as questionable. The most notable are cornerback Levi Wallace (ankle) and edge defender Shaq Lawson (hamstring). Lawson is one of the best pass-rushers and is second on the team in quarterback pressures and sacks. His potential absence would be good news for Deshaun Watson.

Meanwhile, the Texans welcome back J.J. Watt (pec), who has been activated off injured reserve and practiced in full on Thursday.

Houston remains banged up in the secondary, however, with cornerbacks Bradley Roby (hamstring) and Johnathan Joseph (hamstring) listed as questionable. They practiced in a limited fashion all week, suggesting they’re trending toward playing.

Will Fuller (hamstring) also practiced in full all week, but head coach Bill O’Brien said the wide receiver is a game-time decision. Justin Bailey

Sean Koerner’s Projected Odds

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