USC (W) vs. Clemson (W) Odds & Betting Predictions - March 21, 2026

USC (W) at Clemson (W)

7:30 pm • ESPN2

USC Trojans

@

Clemson Tigers

MatchupOpenSpreadTotalMoneyline
USC (W) 17-13	-6.5	-6.5-102	o120.5-110	-275
Clemson (W) 21-11	u120.5	+6.5-118	u120.5-110	+220

location pin

Saturday 7:30 p.m.

March 21, 2026

Colonial Life ArenaColumbia

NCAAW Public Betting

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson (W)	N/A	N/A	N/A	N/A	N/A
USC (W)	N/A	N/A	N/A	N/A	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson (W)	N/A	N/A	N/A	N/A	N/A
USC (W)	N/A	N/A	N/A	N/A	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson (W)	21-11	N/A	N/A	N/A	N/A
USC (W)	3-1	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Mar 6th	@DUKE (W)	L 46-60	+12.5 L	U 125.5	DUKE (W) +551
Mar 5th	@UVA (W)	W 63-50	+2.5 W	U 127.5	CLEM (W) +124
Mar 1st	@STAN (W)	L 50-85	+1.5 L	O 121.5	STAN (W) +105
Feb 27th	@CAL (W)	W 70-63	+4.5 W	O 124.5	CLEM (W) +159
Feb 22nd	DUKE (W)	W 53-51	+12.5 W	U 126	CLEM (W) +540

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See more NCAAW Odds

MatchupOverUnder
USC (W) 17-13	N/A	N/A
Clemson (W) 21-11	N/A	N/A