The UEFA Champions League has reached its first true turning point: the knockout phase. With the "league phase" safety net gone, the European giants face high-stakes, two-legged battles for survival. The margin for error has vanished as teams fight to secure a spot in the next round. The road to Budapest is now at its most treacherous.
We have four games to target on Wednesday's Champions League schedule, and our staff has come up with picks for all of them. Continue reading for our Champions League best bets for Wednesday, February 25.
Champions League Best Bets
The club logos in the table below represent each match that our soccer betting staff is targeting from today's games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Match | Time (ET) | Pick |
|---|---|---|
  | 12:45 p.m. | |
  | 3 p.m. | |
  | 3 p.m. | |
  | 3 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our soccer Odds page, which automatically surfaces the best lines for every game. | ||
Borussia Dortmund vs. Atalanta
Atalanta comes into this game knowing they need at least two goals to remain in the Champions League. The Italian side has exceptional attacking output at home, but they face a Dortmund side that has looked lethal of late.
Atalanta have scored in all seven of their home matches in 2026, netting an average of 2.29 goals per game. Meanwhile, Dortmund have scored in nine of their last 10 away matches across all competitions. Over that period, Niko Kovac’s side has scored an average of 1.6 goals per game and conceded 1.5.
Although Atalanta struggled in the first leg, they will be confident of finding the net this time around, as Dortmund have conceded in all four of their Champions League away matches this season, with opponents netting 3 goals per game on average. Both teams have scored in three of those matches, so this clash promises to be another goal-friendly game.
Pick: Both Teams To Score – Yes
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Galatasaray SK vs. Juventus
Juventus were comprehensively beaten in the first leg. However, they have home advantage this time around, and with Galatasaray having a three-goal lead on aggregate, there is no need for the Turkish side to push for the win.
Galatasaray have a poor away record in Europe of late, with just one win in their last 13 away matches in either the Champions League or the Europa League, losing nine. During that run, they have scored 1.15 goals per game on average, but conceded 2.23. The Turkish side has lost all five matches in which they have been priced over 3.00 on the 1x2 market.
Juventus have suffered just one defeat in 12 competitive home matches under Luciano Spalletti, winning seven. The Old Lady has scored an average of 2.1 goals per game across their last 10 home games, and should have the firepower to beat Galatasaray here.
Pick: Juventus To Win
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AS Monaco vs. Paris Saint-Germain
PSG went two goals behind in the first leg, but managed to come from behind to win 3-2. Luis Enrique’s side thoroughly deserved their victory, finishing the game with 80% possession and having 23 more attempts than Monaco.
Les Parisiens have lost just two of their 16 home matches this season, scoring 2.56 goals per game and conceding 0.83. Meanwhile, Monaco has won just one of their last 10 away games against PSG, losing seven and conceding an average of 3.3 goals.
The Monegasque team has won just six of their 18 away matches across all competitions this season. Their most recent away game in the Champions League was a 6-1 defeat to Real Madrid, and they were similarly priced on the 1x2 market.
Pick: PSG To Win
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S.L. Benfica vs. Real Madrid
Real Madrid may have lost a few crucial games lately and is coming into this match following a 2-1 loss to Osasuna. Meanwhile, Jose Mourinho’s side hit a rough patch on the road, failing to win four of their last six away games across all competitions.
Benfica found a saving 4-2 win in the League Phase, but Los Blancos were on point in Portugal just days ago. Real Madrid allowed the opposition no big chances, while creating four of their own. A similar performance will be more than enough to secure a spot in the final 16.
The visitors need a win to keep themselves in contention. However, Los Blancos have been impressive at home lately, winning six consecutive matches. They’ve conceded goals in four, but outscored the opposition, netting 21 in this six-game span. Real Madrid are rightfully priced as the heavy favourites and will look to make a statement in this intricate matchup.
Pick: Real Madrid To Win
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