As the favorites for the title begin to take shape and the stars of the season take the reins, each new Premier League matchday brings a surge of betting opportunities.
We have four games to target on today's EPL schedule, and our staff has come up clutch with picks in all of them to get the ball rolling. Continue reading for our Premier League best bets for Saturday, October 25.
English Premier League Best Bets
The club logos in the table below represent each match that our soccer betting staff is targeting from today's games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Match | Time (ET) | Pick |
|---|---|---|
  | 10 a.m. | |
  | 10 a.m. | |
  | 12:30 p.m. | |
  | 3 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our soccer Odds page, which automatically surfaces the best lines for every game. | ||
Sunderland vs. Chelsea
By Aleksandar Prokic
After drawing with Brentford and losing consecutive games to United and Brighton, Maresca’s side are back on track with three wins in a row. The Blues kept two clean sheets in these three, and have conceded just 0.79 goals per game at home in the Premier League in 2025. With a newfound defensive stability, the Blues will offer a decent challenge to Sunderland’s attack.
At the same time, the Black Cats are getting most of their goals at home. They’re struggling on the road. When playing away, Sunderland averages just 0.25 goals per game. Regis Le Bris’ team failed to score in three out of four away games, only managing a single goal against Nottingham Forest. Even with numerous injuries and suspensions piling up for Maresca, finding the net will be nearly impossible for them.
Our internal prediction model, BETSiE, projects 0.74 goals for the hosts. However, Sunderland's offensive struggles suggest Chelsea may keep a clean sheet, making the BTS – No bet the value bet in this matchup.
Pick: Chelsea to Win & BTS – No (+120)
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Fulham vs. Newcastle United
By Aleksandar Prokic
Newcastle is currently one of the Premier League's most underperforming teams. After eight games, the Magpies sit in 14th place, just ahead of Fulham. However, based on expected points, Eddie Howe’s team should be in the top four. This team has 4.70 fewer points than it should have, according to the underlying data. When playing at home, Newcastle scores an average of 1.5 goals per game, compared to just 0.75 goals when away.
Fulham’s stats this season indicate they are also struggling away from home, having lost three of four games and managed just a single point, the second-worst in the league. However, they consistently manage to find the net. This trait makes them a threat. The Cottagers have proven they can hit back, even against more formidable opposition, as seen in their narrow loss to Arsenal.
Despite a lower xG, Fulham can capitalize on any defensive lapses from Newcastle, especially given the attacking flair of players like Raul Jimenez, if fit. The last two matches show this fixture is becoming more competitive, with both teams scoring in both.
Pick: Newcastle to Win & BTS – Yes (+260)
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Brighton & Hove Albion vs. Manchester United
By Aleksandar Prokic
Both Brighton and Manchester kicked off the season in poor form, but are now finding wins even as outsiders. They have each pulled off two upsets in their last five matches and find themselves sitting toe-to-toe in the Premier League table, occupying 9th and 10th place, respectively.
Regardless, Ruben Amorim’s team concedes on average 1.0 goals even at Old Trafford, while Brighton has the highest percentage of both teams scoring, with only a single game not seeing goals on both ends.
All trends indicate this will be an open game, and BETSiE agrees with the estimate, expecting a total of 3.17 goals. Based on BETSiE’s predictions, this is also the most likely match to see both teams score, with a 62.8% chance.
Pick: BTS – Yes & Over 2.5 Goals (-138)
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Liverpool vs. Brentford
By Aleksandar Prokic
Something went wrong for Liverpool after the international break, and we can point out a few things. The main reason, however, is the unsettled starting 11, with Arne Slot struggling to settle on a standard lineup.
The integration of new signings has been inconsistent, leading to a lack of cohesion and stability. Individual errors and tactical decisions have led to goals against. There is an evident hole in Liverpool’s right side, and the Bees will look to use this to their advantage. Playing at home, Keith Andrews’s team has a decent chance of doing some damage.
BETSiE expects goals on both ends, estimating a 58.6% chance of BTTS – Yes winning. While team play is lacking, the Reds have enough individual talent to end the losing streak.
Pick: Liverpool to Win & BTS – Yes
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