Napoli vs. PSV Odds & Betting Predictions - October 21, 2025

Napoli at PSV

7:00 pm

SSC Napoli

1-2

2

2 - 6

PSV Eindhoven

1-1-1

6

MatchupOpenSpreadTotalMoneyline
Napoli 1-2	-0.5	-0.5+110	o2.5-156	+120
PSV 1-1-1	u2.5	+0.5-155	u2.5+121	+220

location pin

Tuesday 7:00 p.m.

October 21, 2025

Philips Stadion

Today's Champions League Best Bets
Action Network Staff•
Oct 21, 2025 UTC

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Champions League Public Betting

PSV are 1-1 in their last 5 games.
PSV are 2-1 in their last 5 games against the spread
PSV are 1-0 in their road games against the spread
The totals have gone OVER in 2 of PSV' last 3 games
The totals have gone OVER in 2 of PSV' 2 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
PSV	2-1	1-1	1-0	0-1	2-0
Napoli	1-2	1-0	0-2	1-1	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
PSV	2-1	2-0	0-1	1-0	1-1
Napoli	2-1	1-0	1-1	2-0	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
PSV	1-1	1-1	0-0-1	0-1	1-0-1
Napoli	1-2	1-0	0-2	1-1	0-1

date	opponent	score	spread	over/under	moneyline
Oct 1st	@LEV	L 1-1	+0.5 W	U 3.5	LEV +290
Sep 16th	USG	L 1-3	-0.5 L	O 2.5	USG -118
Mar 12th	@ARS	L 2-2	+1 W	O 2.5	ARS +540
Mar 4th	ARS	L 1-7	+0.5 L	O 2.5	ARS +310
Feb 19th	JUV	W 3-1	-0.5 W	O 2.5	PSV +120

Guus Til
MID
Knock
Out Indefinitely

Armando Obispo
DEF
Obispo is doubtful with head
Doubtful

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Napoli

PSV

8

Fouls

11

10

Shots

18

8

Corners

4

1

Offsides

2

1

Red Cards

0

1

Yellow Cards

4

2

Shots On Goal

8

45%

Possession Time

55%

Napoli

Goalkeeping

PSV

Could not load odds

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MatchupOverUnder
Napoli 1-2	o1.5-115	u1.5-120
PSV 1-1-1	o1.5+130	u1.5-185