White Sox vs. Astros Odds & Betting Predictions - September 29, 2026
White Sox at Astros
9:00 pm • PeacockStarting Pitchers
| pitcher | team | era | w-l |
|---|
White Sox at Astros Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
White Sox 84-78 | +1.5 | +1.5-184 | o8.5-109 | +115 |
Astros 81-81 | u8 | -1.5+153 | u8.5-108 | -135 |

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White Sox vs. Astros Expert Picks
Doug Ziefel
Last 30d: 338-368-11 (+7.7u)
CWS +120
0.42u

Sean Zerillo
Last 30d: 52-71-2 (-8.1u)
Under 8.5-122
0.61u
Bet to 8 (-118)
Prop Odds Comparison
Line Movement Tracker
White Sox vs. Astros Public Betting Percentages
Betting Trends
- Astros are 3-2 in their last 5 games.
- Astros are 3-2 in their last 5 games against the spread
- Astros are 45-36 in their road games against the spread
- The totals have gone OVER in 1 of Astros' last 5 games
- The totals have gone OVER in 36 of Astros' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
White Sox vs. Astros Injury Updates

White Sox Injuries
- Mike VasilRP
Vasil is out with elbow
Out
- Ky BushSP
Bush is out with elbow
Out
- Brooks BaldwinLF
Baldwin is out with elbow
Out
- Drew ThorpeSP
Thorpe is out with elbow
Out

Astros Injuries
White Sox vs. Astros Odds Comparison
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White Sox at Astros Team Totals
MatchupOverUnder | ||
|---|---|---|
White Sox 84-78 | N/A | N/A |
Astros 81-81 | N/A | N/A |
