White Sox vs. Astros Odds & Betting Predictions - September 29, 2026

White Sox at Astros

9:00 pm • Peacock
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Starting Pitchers
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White Sox at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
White Sox
84-78
+1.5
+1.5-184
o8.5-109
+115
Astros
81-81
u8
-1.5+153
u8.5-108
-135
location pinTuesday 9:00 p.m.
September 29, 2026
Daikin ParkHouston
thermometer image89°Fahrenheit
rain image4%Rain
wind image11Wind
White Sox vs. Astros Expert Picks
Doug Ziefel
Doug Ziefel
Last 30d: 338-368-11 (+7.7u)
CWS +120
0.42u
Sean Zerillo
Sean Zerillo
Last 30d: 52-71-2 (-8.1u)
Under 8.5-122
0.61u
Bet to 8 (-118)

Prop Odds Comparison

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Line Movement Tracker

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White Sox vs. Astros Public Betting Percentages

Away Logo

White Sox

Public

30%

Bets%

70%

Money%

MLB Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros
82-8037-4445-3643-6039-18
White Sox
94-6847-3447-340-292-66

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros
72-83-736-43-236-40-545-56-225-27-5
White Sox
75-80-742-34-533-46-20-273-78-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros
81-8146-3541-4056-4731-26
White Sox
84-7833-4827-541-158-100

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 27th@ATHW 9-0-1.5 WU 10.5HOU -199
Sep 27th@ATHW 13-2-1.5 WO 10HOU -165
Sep 26th@ATHL 5-6-1.5 LO 9.5ATH -200
Sep 25th@ATHW 7-5-1.5 WO 11HOU -180
Sep 24th@SEAL 5-6+1.5 WO 7.5SEA +110

White Sox vs. Astros Injury Updates

White Sox Injuries

  • Mike Vasil
    RP

    Vasil is out with elbow

    Out

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Brooks Baldwin
    LF

    Baldwin is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Astros Injuries

    White Sox vs. Astros Odds Comparison

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    White Sox at Astros Team Totals

    MatchupOverUnder
    White Sox
    84-78
    N/A
    N/A
    Astros
    81-81
    N/A
    N/A