The Memphis Grizzlies (24-45) and Charlotte Hornets (36-34) will meet in the NBA tonight. Tipoff is set for 7:00 p.m. ET from the Spectrum Center in Charlotte, North Carolina. The game will broadcast live on FDSSE.
The Hornets are 16.5-point favorites over the Grizzlies on the spread (Hornets -16.5), with the over/under set at 235.5 total points. Charlotte is a -1400 favorite to win outright on the moneyline, while Memphis is +775 to pull off the upset.
Let's get into our Grizzlies vs. Hornets predictions and NBA picks for Saturday, March 21.
- Grizzlies vs Hornets pick: Over 235.5 (-105)
Our Hornets vs. Grizzlies best bet is on the game to go Over 235.5 total points. Make sure to find the best odds by checking our live NBA odds page.
Grizzlies vs Hornets Odds
| Grizzlies Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+16.5 -110 | 235.5 -105o / -115u | +775 |
| Hornets Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-16.5 -110 | 235.5 -105o / -115u | -1400 |
Grizzlies vs Hornets NBA Preview
The Grizzlies are in full-tank mode with most of their key players sidelined — with Ja Morant, Santi Aldama, Kentavious Caldwell-Pope, Scotty Pippen Jr., Zach Edey, and Brandon Clarke all out for the foreseeable future.
So, it is easy to see why the Grizzlies have lost nine of their last 10 games and are probably content to keep up their poor performance.
Most importantly though, they have been consistently producing high scores. Grizzlies' games have totaled more than 235.5 points in seven of their past nine contests.
Plus, the Hornets have also surpassed this line in their last two games, both at home, where this matchup versus Memphis will take place as well. Brandon Miller, LaMelo Ball and Kon Knueppel scored 16+ points in each of those games.
Our Bet Labs "Bad Road Overs (V2)" system recommends sticking with that trend and going with the over in tonight's matchup.
Grizzlies vs Hornets Predictions, Betting Analysis
This NBA totals betting system focuses on games where struggling road teams face stronger home opponents in non-conference matchups, creating favorable conditions for high scoring results, which appears to be the case in tonight's matchup between Memphis and Charlotte.
When a poor road team with a low win rate such as the Grizzlies meets a winning home team like the Hornets (36-34 overall record), defensive effort and intensity often dip for the visitor while the home side pushes the pace and controls offensive rhythm.
Non-conference games tend to feature looser defensive schemes and unfamiliar matchups, leading to faster scoring runs and less resistance in transition.
The data shows that when totals close above the 220 range and the line movement slightly favors the Over, the market correctly anticipates offensive efficiency rather than defensive pressure.
These situations consistently produce games where both teams exceed expectations, with the stronger home team dictating tempo and the weaker visitor contributing enough to push the total past the number.
Pick: Over 235.5 (-105, BetMGM)




















