White Sox vs Guardians Game 2 ALDS is here, and this White Sox vs Guardians prediction rounds up the best MLB player props today straight from the live Polymarket board.
- The White Sox arrive 1-0 in this ALDS after a Game 1 road win, extending the momentum from their first playoff series win since 2005 in the Wild Card round.
- The Guardians sit 0-1 at home and need to answer back at Progressive Field after winning the AL Central by a single game over Chicago in the regular season.
Here is our full picks table before we break down every editor's pick, the game lines, and every player prop board for Game 2.
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It |
|---|---|---|---|
| Sam Antonacci 1+ Hits | Yes | 63¢ | $154.06 | Trade it on Polymarket! |
| Jo Adell 1+ Hits | Yes | 60¢ | $162.16 | Trade it on Polymarket! |
| Gavin Williams 8+ Strikeouts | Yes | 51¢ | $189.62 | Trade it on Polymarket! |
| Steven Kwan 2+ Hits + Runs + RBIs | Yes | 51.54¢ | $187.68 | Trade it on Polymarket! |
| Gavin Williams 2+ Earned Runs Allowed | Yes | 43¢ | $223.69 | Trade it on Polymarket! |
| Chase DeLauter 2+ Total Bases | Yes | 38.96¢ | $246.20 | Trade it on Polymarket! |
| Miguel Vargas 1+ RBIs | Yes | 27¢ | $352.48 | Trade it on Polymarket! |
| Munetaka Murakami 1+ HR | Yes | 18¢ | $525.61 | Trade it on Polymarket! |
| José Ramírez 1+ HR | Yes | 12¢ | $785.33 | Trade it on Polymarket! |
Best MLB Player Props Today for CWS vs CLE (Game 2)
Every pick below is a real trade we'd make after redeeming the Polymarket promo code (ACTION), part of our best MLB player props today for this ALDS Game 2 matchup.
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Best Hits Prop Today – Sam Antonacci 1+ Hits
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Sam Antonacci 1+ Hits | Yes | 63¢ | $154.06 | Trade it now on Polymarket! |
Antonacci has settled into an everyday left field role for a White Sox lineup that's been scorching hot since the final week of the regular season.
Cleveland hands the ball to Gavin Williams, a power arm who racked up 248 strikeouts this year but has actually struggled against this specific White Sox lineup, going 1-3 in four starts versus Chicago this season.
At a $100 buy near 63 cents, this works out to roughly 158 shares, and the gap between that raw share value and Polymarket's stated $154.06 payout reflects normal order book depth and fees, not an error.
- If Antonacci records a hit: profit of $154.06.
- If he doesn't: the $100 stake is a total loss.
A short price, but still a little better than 1.5-to-1 on a player seeing everyday at-bats.
Best Hits Prop Today – Jo Adell 1+ Hits
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Jo Adell 1+ Hits | Yes | 60¢ | $162.16 | Trade it now on Polymarket! |
Adell has slotted into the middle of Cleveland's lineup since arriving at the trade deadline, and he's a lock for everyday reps in a series this important.
Chicago counters with Kay on the mound, and while the lefty has been steady all year, Adell's raw bat-to-ball tools give him a real path to a hit even in a tough matchup.
At a $100 buy near 60 cents, this works out to roughly 167 shares, with Polymarket's stated payout at $162.16.
- If Adell records a hit: profit of $162.16.
- If he doesn't: the $100 stake is a total loss.
Another short price that still returns well over 1.5x the stake.
Best Strikeouts Prop Today – Gavin Williams 8+ Strikeouts
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Gavin Williams 8+ Strikeouts | Yes | 51¢ | $189.62 | Trade it now on Polymarket! |
Williams finished the season with 248 strikeouts and a 3.76 ERA, the kind of swing-and-miss stuff that travels well into October.
The White Sox have had his number on the scoreboard this year, but that success has come in spite of, not because of, a shaky bat-to-ball approach against his power arsenal.
At a $100 buy near 51 cents, this works out to roughly 196 shares, with a stated payout of $189.62.
- If Williams strikes out 8 or more: profit of $189.62.
- If he doesn't: the $100 stake is a total loss.
Essentially a coin flip number that still nearly doubles the stake.
Best Combo Prop Today – Steven Kwan 2+ Hits + Runs + RBIs
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Steven Kwan 2+ Hits + Runs + RBIs | Yes | 51.54¢ | $187.68 | Trade it now on Polymarket! |
Kwan is Cleveland's table-setter at the top of the order, and a combo prop like this plays to his profile as a high-contact bat who's also in scoring position often.
With the Guardians needing to atone for dropping Game 1 at home, expect Kwan to see a heavy diet of pitches to hit early in this one.
At a $100 buy near 51.54 cents, this works out to roughly 194 shares, with a stated payout of $187.68.
- If Kwan reaches 2 or more combined hits, runs, and RBIs: profit of $187.68.
- If he doesn't: the $100 stake is a total loss.
A near coin-flip price on a player who touches the stat sheet in multiple ways.
Best Earned Runs Allowed Prop Today – Gavin Williams 2+ Earned Runs Allowed
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Gavin Williams 2+ Earned Runs Allowed | Yes | 43¢ | $223.69 | Trade it now on Polymarket! |
Despite the strikeout totals, Williams has been genuinely hittable against this exact White Sox lineup, going 1-3 in his four regular-season starts against Chicago.
A White Sox offense that scored 41 runs in the final week of the regular season isn't likely to go quietly, even against a pitcher with this much swing-and-miss equity.
At a $100 buy near 43 cents, this works out to roughly 233 shares, with a stated payout of $223.69.
- If Williams allows 2 or more earned runs: profit of $223.69.
- If he doesn't: the $100 stake is a total loss.
A longer shot than his strikeout number, but the payout still covers more than double the stake.
Best Total Bases Prop Today – Chase DeLauter 2+ Total Bases
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Chase DeLauter 2+ Total Bases | Yes | 38.96¢ | $246.20 | Trade it now on Polymarket! |
DeLauter has emerged as a real power threat in Cleveland's outfield, and a 2+ total bases number gives him multiple paths to cash, from a double to any extra-base knock.
Facing a White Sox staff that's been riding momentum more than dominant stuff, there's a real path to DeLauter getting his against Kay or whoever follows out of the bullpen.
At a $100 buy near 38.96 cents, this works out to roughly 257 shares, with a stated payout of $246.20.
- If DeLauter clears 2 total bases: profit of $246.20.
- If he doesn't: the $100 stake is a total loss.
A true longshot number that still pays out nearly 2.5x the stake.
Best RBI Prop Today – Miguel Vargas 1+ RBIs
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Miguel Vargas 1+ RBIs | Yes | 27¢ | $352.48 | Trade it now on Polymarket! |
Vargas has carved out a run-producing role in Chicago's order, and a lineup this hot should keep giving him chances to drive in a run.
Cleveland's bullpen questions, with Colin Holderman and Rhys Hoskins both working back from injury, only add to the uncertainty for a White Sox offense looking to keep pouring it on.
At a $100 buy near 27 cents, this works out to roughly 370 shares, with a stated payout of $352.48.
- If Vargas drives in a run: profit of $352.48.
- If he doesn't: the $100 stake is a total loss.
A real longshot price, but the payout here is better than 3.5-to-1.
Best Home Run Prop Today – Munetaka Murakami 1+ Home Run
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| Munetaka Murakami 1+ HR | Yes | 18¢ | $525.61 | Trade it now on Polymarket! |
Murakami's rookie season has been one of the stories of the year in the American League, and he's been a middle-of-the-order fixture for a White Sox lineup that's carried its hot streak straight into October.
Williams has swing-and-miss stuff, but he's also shown he can be hit hard by this exact lineup, which keeps Murakami's raw power squarely in play tonight.
At a $100 buy near 18 cents, this works out to roughly 556 shares, and the gap between that raw share value and the stated $525.61 payout reflects normal order book depth and fees, not an error.
- If Murakami goes deep: profit of $525.61.
- If he doesn't: the $100 stake is a total loss.
A true longshot swing, but the payout multiple here is better than 5-to-1.
Best Home Run Prop Today – José Ramírez 1+ Home Run
| ⚾ Game 2 Prediction | 🏷️ Position | Price | 🤑 Profit on $100 | 📈 Trade It Now |
|---|---|---|---|
| José Ramírez 1+ HR | Yes | 12¢ | $785.33 | Trade it now on Polymarket! |
Ramírez remains the engine of Cleveland's lineup and the one hitter the Guardians need to carry them after dropping Game 1 at home.
Kay is a left-hander, and while Ramírez has had success against lefties throughout his career, a true all-or-nothing home run swing is always a longer shot regardless of the matchup.
At a $100 buy near 12 cents, this works out to roughly 833 shares, with a stated payout of $785.33.
- If Ramírez goes deep: profit of $785.33.
- If he doesn't: the $100 stake is a total loss.
The deepest longshot on the board tonight, but the payout multiple is nearly 8-to-1.
White Sox vs Guardians Moneyline
Before the board dives into player props, here's where this White Sox vs Guardians prediction stands on the base game lines for Game 2.
White Sox Moneyline
Chicago is priced as the road underdog, sitting at 41% to win outright as it tries to push the series lead to 2-0.
Guardians Moneyline
Cleveland is the home favorite at 60% to win outright, needing a response at Progressive Field to even this ALDS at a game apiece.
Spread and Total for White Sox vs Guardians
Cleveland is laying a run and a half tonight, and the total sits close to the middle of the board.
White Sox vs Guardians Spread
Cleveland to win by more than 1.5 runs is priced at 38% Yes against 62% No on the White Sox staying within a run and a half.
White Sox vs Guardians Total
The total sits at 6.5 runs, priced at 50% Yes on the over against 50% No on the under, a true pick'em.
Home Run Predictions Today for CWS vs CLE
Our home run predictions today cover both power hitters Polymarket has priced for this specific home run market in Game 2.
- Munetaka Murakami (CWS) (1+ Home Run: Yes 18%): the rookie slugger anchoring Chicago's middle of the order.
- José Ramírez (CLE) (1+ Home Run: Yes 12%): Cleveland's franchise cornerstone and the lineup's biggest threat.
Hits Props for White Sox vs Guardians
- Sam Antonacci (CWS) (1+ Hits: Yes 63%): an everyday left fielder riding Chicago's hot streak.
- Jo Adell (CLE) (1+ Hits: Yes 60%): a trade deadline addition now entrenched in Cleveland's lineup.
Total Bases Props
- Chase DeLauter (CLE) (2+ Total Bases: Yes 38%): a developing power bat in the Guardians outfield.
Combo Stat Props
- Steven Kwan (CLE) (2+ Hits + Runs + RBIs: Yes 47%): Cleveland's high-contact table-setter at the top of the order.
RBI Props
- Miguel Vargas (CWS) (1+ RBIs: Yes 27%): a run-producing bat in the middle of Chicago's surging order.
Strikeout Props
- Gavin Williams (CLE) (8+ Strikeouts: Yes 51%): a 248-strikeout arm with swing-and-miss stuff all season.
Earned Runs Allowed Props
- Gavin Williams (CLE) (2+ Earned Runs Allowed: Yes 43%): a power arm who's nonetheless been hittable against this exact White Sox lineup.
What's Moving the Market
Prediction markets and prices can move for several reasons. This week, our best MLB player props today lean on two things: Chicago's red-hot offense carrying its Wild Card momentum into the ALDS, and Cleveland's bullpen uncertainty with Colin Holderman and Rhys Hoskins both working back from injury.
That same lineup strength is exactly why our home run predictions today and hits props skew toward the White Sox side of this CWS vs CLE board, even on the road.
Early action has the total ticking down slightly on the over, a sign the market may be leaning toward Williams' strikeout stuff slowing down the scoring compared to Game 1.
How to Trade This Board on Polymarket
Ready to get in on these White Sox vs Guardians picks yourself? Here's exactly how to claim the bonus and start trading tonight's board:
- Read a comprehensive Polymarket review to understand how this exchange operates.
- Follow this guide to trading on Polymarket to learn how to buy your first "Yes" or "No" contract.
- Monitor the relevant tab on Polymarket to stay ahead of the live order book movements.
- When you're ready, sign up with Polymarket promo code ACTION to get started!
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Final Thoughts: Best Home Run Bets Today for CWS vs CLE
Chicago's momentum is real, but Cleveland still has the deeper rotation and a franchise cornerstone in José Ramírez capable of flipping this series back in its favor at home.
Williams' strikeout stuff makes him a threat to slow the White Sox bats down, even though this exact lineup has given him trouble all season.
That wraps our full White Sox vs Guardians prediction and every best MLB player props today pick we'd make on the Polymarket board for Game 2.
White Sox vs Guardians Prediction FAQs
Who wins the White Sox vs Guardians prediction tonight?
The Polymarket board favors Cleveland at 60% to win outright at home, with the Guardians also laying 1.5 runs on the spread.
What are the best MLB player props today for this game?
Our top plays lean on Sam Antonacci and Jo Adell's hits floors, plus Gavin Williams' strikeout upside on the mound for Cleveland.
What are the home run predictions today for CWS vs CLE?
Munetaka Murakami and José Ramírez are the two home run props priced on this board, with Murakami the shorter price of the pair.
How do I use promo code ACTION on Polymarket?
Create an account, make a qualifying deposit, and enter code ACTION to unlock a trading bonus before first pitch.
What time does White Sox vs Guardians Game 2 start?
Game 2 of this ALDS is played at Progressive Field in Cleveland, with national coverage on TBS, truTV, and Univision/TUDN.
Is there a Guardians pick on this home run board?
Yes, José Ramírez represents Cleveland's side of the home run market, priced as the deeper longshot of the two picks here.
