Trey Sermon & Kyle Juszczyk Fantasy Football Advice With Elijah Mitchell Out in Week 4

Welcome to what's becoming a weekly feature on Sunday mornings: Trying to figure out what to do in fantasy football with San Francisco 49ers running backs.

Week 1 standout Elijah Mitchell will not play for a second consecutive week due to a shoulder injury. That leaves managers left to wonder who to play on Sunday morning.

Rookie Trey Sermon led the team with 10 carries in a 30-28 loss to the Green Bay Packers in Week 3 in addition to two receptions. He ran for 31 yards and a touchdown.

Meanwhile, Kyle Juszczyk only carried the ball five times but caught four passes for nine total touches. Five other players contributed a rush attempt, including George Kittle, Deebo Samuel and Trey Lance.

In Sermon's one game as the lead back, he received only 10 carries (of the team's 21) and played 59% of the snaps — fewer snaps than fullback Juszczyk, who often lined up as the tailback in place of Sermon on key plays.

With Mitchell out, Sermon sits in Tier 7 of The Action Network fantasy analyst Sean Koerner's fantasy football tiers.

Koerner has a consensus ranking of 21 for running backs in standard scoring leagues. On "Convince Me!", fantasy analyst Samantha Previte called Sermon a "high-end flex play."

But Juszczyk might be an option in deeper leagues as well. Fantasy expert Chris Raybon is higher on the fullback than Koerner, ranking him RB34 in standard scoring leagues.

The 49ers are 2.5-point favorites over the Seattle Seahawks with a total of 52.