Astros vs. Cardinals Odds & Betting Predictions - March 18, 2026

Astros at Cardinals

5:05 pm • SCHN

Houston Astros

@

St. Louis Cardinals

pitcher		team	era	w-l

MatchupOpenSpreadTotalMoneyline
Astros 9-10	N/A	N/A	N/A
Cardinals 11-9	N/A	N/A	N/A

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Wednesday 5:05 p.m.

March 18, 2026

Roger Dean StadiumJupiter

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70°Fahrenheit

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0%Rain

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13Wind

No props found

MLB Public Betting

Cardinals are 1-4 in their last 5 games.
Cardinals are 1-4 in their last 5 games against the spread
Cardinals are 39-42 in their road games against the spread
The totals have gone OVER in 3 of Cardinals' last 5 games
The totals have gone OVER in 39 of Cardinals' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	80-82	41-40	39-42	25-42	54-40
Astros	82-80	37-44	45-36	43-60	39-18

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	81-74-7	39-39-3	42-35-4	33-29-5	47-45-2
Astros	72-83-7	36-43-2	36-40-5	45-56-2	25-27-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	78-84	44-37	34-47	33-34	44-50
Astros	87-75	46-35	41-40	56-47	31-26

date	opponent	score	spread	over/under	moneyline
Mar 14th	@MIA	L 7-7	-	-	-
Mar 13th	HOU	W 5-4	+1.5 W	O 8.5	STL +110
Mar 12th	NYM	W 3-1	+1.5 W	U 10	STL +114
Mar 11th	@WSH	L 1-3	-1.5 L	U 7.5	WSH -115
Mar 10th	@NYM	L 1-6	+1.5 L	U 7.5	NYM +148

Hayden Wesneski
RP
Wesneski is out with elbow
Out

Masyn Winn
SS
Masyn Winn (knee) has been scratched Friday.
Out

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MatchupOverUnder
Astros 9-10	N/A	N/A
Cardinals 11-9	N/A	N/A