Cubs vs. White Sox Odds & Betting Predictions - July 25, 2025

Cubs at White Sox

11:40 pm • CHSN
5 - 12
Starting Pitchers
pitcherteameraw-l
Adrian Houser logoA.HouserChicago White Sox logo2.106-2
Shota Imanaga logoS.ImanagaChicago Cubs logo3.127-4

Cubs at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
60-43
-1.5
-1.5-111
o8-112
-186
White Sox
38-66
u8.5
+1.5-108
u8-110
+154
location pinFriday 11:40 p.m.
July 25, 2025
Rate FieldChicago
Cubs vs. White Sox Expert Picks
Al’s Analytics
Al’s Analytics
Last 30d: 46-41-0 (+3.3u)
CHC -1-125
1u
Low Starter ERA In Interleague Game vs RHP 132-42 (75.9%) 22.97% ROI 11-3 in 2025 Cubs As Bounce Back Favorites 53-19 (73.6%) 28.39% ROI 23-5 in 2025

Cubs vs. White Sox Previews & Analysis

  • Cubs vs White Sox: First Five Innings Bet for Tonight article feature image

    Cubs vs White Sox: First Five Innings Bet for Tonight

    Action Network Staff
    Jul 25, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Cubs vs. White Sox Public Betting Percentages

Away Logo

Cubs

Public

86%

Bets%

14%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
60-4429-2231-220-260-42
Cubs
51-5225-2726-2538-3313-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
46-54-427-21-319-33-10-246-52-4
Cubs
52-46-528-22-224-24-335-33-317-13-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
38-6622-2916-371-137-65
Cubs
60-4333-1927-2448-2312-20

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jul 23rd@TBW 11-9+1.5 WO 9CWS +182
Jul 22nd@TBL 3-4+1.5 WU 8.5TB +194
Jul 21st@TBW 8-3+1.5 WO 9CWS +180
Jul 20th@PITW 7-2+1.5 WU 9.5CWS +119
Jul 19th@PITW 10-4+1.5 WO 8CWS +118

White Sox vs. Cubs Injury Updates

White Sox Injuries

  • Ryan Noda
    1B

    Noda is out with quad

    Out

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

  • Shane Smith
    SP

    Smith is out with ankle

    Out

Cubs Injuries

  • Jameson Taillon
    SP

    Taillon is out with calf

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

Cubs vs. White Sox Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Shota Imanaga logoLS.Imanaga, P85327
Chris Flexen logoRC.Flexen, P47223
Drew Pomeranz logoLD.Pomeranz, P18120
Ryan Brasier logoRR.Brasier, P19120
Jon Berti logoRJ.Berti, P16101
HITTERSH-ABRHRRBI
Michael Busch logo1M.Busch, 1B0-4000
Kyle Tucker logo2K.Tucker, RF1-4001
Seiya Suzuki logo3S.Suzuki, DH0-2000
Jon Berti logo3J.Berti, PH0-2000
Pete Crow-Armstrong logo4P.Crow-Armstrong, CF0-3100
Ian Happ logo5I.Happ, LF0-2100
Matt Shaw logo5M.Shaw, 2B1-1100
Dansby Swanson logo6D.Swanson, SS0-2000
Justin Turner logo6J.Turner, PH0-2000
Justin Turner logo6J.Turner, 3B0-2000
Nico Hoerner logo7N.Hoerner, 2B1-4100
Nico Hoerner logo7N.Hoerner, SS1-4100
Reese McGuire logo8R.McGuire, C3-4114
Vidal Brujan logo9V.Brujan, 3B3-4000
Vidal Brujan logo9V.Brujan, LF3-4000
White Sox Player Stats
Projected
PITCHERPCIPKER
Adrian Houser logoRA.Houser, P836.233
Tyler Gilbert logoLT.Gilbert, P151.100
Steven Wilson logoRS.Wilson, P28112
HITTERSH-ABRHRRBI
Chase Meidroth logo1C.Meidroth, SS3-5311
Austin Slater logo2A.Slater, LF2-5311
Edgar Quero logo3E.Quero, C4-5201
Andrew Benintendi logo4A.Benintendi, DH1-5001
Miguel Vargas logo5M.Vargas, 1B3-4101
Josh Rojas logo5J.Rojas, 2B0-0100
Lenyn Sosa logo6L.Sosa, 2B2-4003
Lenyn Sosa logo6L.Sosa, 1B2-4003
Mike Tauchman logo7M.Tauchman, RF1-4112
Brooks Baldwin logo7B.Baldwin, RF0-1001
Michael A. Taylor logo8M.Taylor, CF1-5000
Colson Montgomery logo9C.Montgomery, 3B1-4111

Cubs vs. White Sox Odds Comparison

Right Arrow

Could not load odds

Cubs at White Sox Team Totals

MatchupOverUnder
Cubs
60-43
o4.5-120
u4.5-108
White Sox
38-66
o3.5+111
u3.5-141