Guardians vs. Giants Odds & Betting Predictions - March 21, 2026

Guardians at Giants

7:05 pm • SF Video

Cleveland Guardians

@

San Francisco Giants

pitcher		team	era	w-l
T.Bibee			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Guardians 13-12	N/A	N/A	N/A
Giants 17-9	N/A	N/A	N/A

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Saturday 7:05 p.m.

March 21, 2026

Scottsdale StadiumScottsdale

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96°Fahrenheit

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0%Rain

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3Wind

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MLB Public Betting

Giants are 4-1 in their last 5 games.
Giants are 3-2 in their last 5 games against the spread
Giants are 41-40 in their road games against the spread
The totals have gone OVER in 2 of Giants' last 5 games
The totals have gone OVER in 35 of Giants' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	76-86	35-46	41-40	35-57	40-28
Guardians	86-76	39-42	47-34	33-36	51-38

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	75-80-7	35-45-1	40-35-6	36-55-1	37-25-6
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	81-81	42-39	39-42	49-43	31-37
Guardians	88-74	45-36	43-38	44-25	43-46

date	opponent	score	spread	over/under	moneyline
Mar 20th	@COL	W 14-11	-1.5 W	O 11.5	SF -150
Mar 18th	@LAD	L 1-5	+1.5 L	U 11.5	LAD +130
Mar 16th	@SD	L 1-3	+1.5 L	U 11	SD +102
Mar 15th	MIL	W 7-1	-1.5 W	U 11.5	SF -134
Mar 14th	ARI	L 7-8	-1.5 L	O 11.5	ARI -130

JT Brubaker
RP
Brubaker is out with ribs
Out
Reiver Sanmartin
RP
Sanmartin is out with elbow
Out

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MatchupOverUnder
Guardians 13-12	N/A	N/A
Giants 17-9	N/A	N/A