White Sox vs. Diamondbacks Odds & Betting Predictions - April 22, 2026

White Sox at Diamondbacks

1:40 am • CHSN

Chicago White Sox

@

Arizona Diamondbacks

pitcher		team	era	w-l
M.Kelly			0.00	0-0
S.Burke			0.00	0-0

MatchupOpenSpreadTotalMoneyline
White Sox 7-14	N/A	N/A	N/A
Diamondbacks 13-8	N/A	N/A	N/A

location pin

Wednesday 1:40 a.m.

April 22, 2026

Chase FieldPhoenix

thermometer image

86°Fahrenheit

rain image

0%Rain

wind image

12Wind

No props found

MLB Public Betting

Diamondbacks are 4-1 in their last 5 games.
Diamondbacks are 4-1 in their last 5 games against the spread
Diamondbacks are 10-2 in their road games against the spread
The totals have gone OVER in 3 of Diamondbacks' last 5 games
The totals have gone OVER in 5 of Diamondbacks' 9 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Diamondbacks	17-4	7-2	10-2	5-1	11-3
White Sox	9-12	4-5	5-7	N/A	9-12

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Diamondbacks	12-8-1	5-4	7-4-1	3-3	8-5-1
White Sox	13-8	5-4	8-4	N/A	13-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Diamondbacks	13-8	7-2	6-6	5-1	7-7
White Sox	7-14	3-6	4-8	N/A	7-14

date	opponent	score	spread	over/under	moneyline
Apr 19th	TOR	W 6-2	-1.5 W	U 9	ARI -151
Apr 18th	TOR	W 6-3	-1.5 W	O 8.5	ARI -142
Apr 15th	@BAL	W 8-5	+1.5 W	O 9	ARI +119
Apr 14th	@BAL	W 4-3	+1.5 W	U 8.5	ARI +135
Apr 13th	@BAL	L 7-9	+1.5 L	O 9	BAL +110

Mike Vasil
RP
Vasil is out with elbow
Out
Ky Bush
SP
Bush is out with elbow
Out
Brooks Baldwin
LF
Baldwin is out with elbow
Out
Kyle Teel
C
Teel is out with hamstring
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

Corbin Burnes
SP
Burnes is out with elbow
Out
Blake Walston
SP
Walston is out with elbow
Out
Tyler Locklear
1B
Locklear is out with elbow
Out

Cristian Mena
SP
Mena is doubtful with shoulder
Doubtful

See more MLB Injuries

Could not load odds

See more MLB Odds

MatchupOverUnder
White Sox 7-14	N/A	N/A
Diamondbacks 13-8	N/A	N/A