Louisville vs. Syracuse Odds & Betting Predictions - October 17, 2026
Louisville at Syracuse
11:30 pm • ACC NetworkLouisville at Syracuse Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Louisville 3-3 | -12.5 | -14.5-112 | o55.5-112 | -650 |
Syracuse 2-3 | u55.5 | +14.5-108 | u55.5-108 | +475 |

JMA Wireless DomeSyracuse
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Syracuse Public Betting Percentages
Betting Trends
- Syracuse are 2-3 in their last 5 games.
- Syracuse are 2-3 in their last 5 games against the spread
- Syracuse are 1-2 in their road games against the spread
- The totals have gone OVER in 3 of Syracuse' last 5 games
- The totals have gone OVER in 1 of Syracuse' 2 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 2-3 | 1-1 | 1-2 | 1-2 | 1-1 | |
| 4-2 | 3-1 | 0-1 | 3-2 | 1-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 3-2 | 1-1 | 2-1 | 2-1 | 1-1 | |
| 5-1 | 3-1 | 1-0 | 4-1 | 1-0 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 2-3 | N/A | N/A | 2-1 | 0-2 | |
| 3-3 | N/A | N/A | 3-2 | 0-1 |
Last 5 Matchups
Team Stats
1577
YDS
1408
112/161
Comps/Atts
113/190
9.8
YPA
7.41
10/1
TDs/INTs
12/7
11/78
Sacks/Yards
11/75
18/22 81.8%
Redzone
21/26 80.8%
30/67 0%
3rd Down
36/78 0%
0/4 0%
4th Down
6/11 0%
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Penalties/Yards
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Louisville vs. Syracuse Odds Comparison
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Louisville at Syracuse Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 3-3 | N/A | N/A |
Syracuse 2-3 | N/A | N/A |


