Louisville vs. Syracuse Odds & Betting Predictions - October 17, 2026

Louisville at Syracuse

11:30 pm • ACC Network
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Louisville at Syracuse Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
3-3
-12.5
-14.5-112
o55.5-112
-650
Syracuse
2-3
u55.5
+14.5-108
u55.5-108
+475
location pinSaturday 11:30 p.m.
October 17, 2026
JMA Wireless DomeSyracuse

Prop Odds Comparison

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Line Movement Tracker

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Louisville vs. Syracuse Public Betting Percentages

Away Logo

Louisville

Public

40%

Bets%

60%

Money%

NCAAF Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Syracuse
2-31-11-21-21-1
Louisville
4-23-10-13-21-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Syracuse
3-21-12-12-11-1
Louisville
5-13-11-04-11-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Syracuse
2-3N/AN/A2-10-2
Louisville
3-3N/AN/A3-20-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 10th@UVAL 25-28+14 WO 49.5UVA +440
Oct 3rd@UCONNW 42-41-6.5 LO 51.5SYR -260
Sep 17th@PITTL 13-27+10.5 LU 51.5PITT +330
Sep 12thCALL 18-21-4 LU 56.5CAL -198
Sep 5thNHW 66-3-35.5 WO 56.5SYR -20000
Team Stats
1577
YDS
1408
112/161
Comps/Atts
113/190
9.8
YPA
7.41
10/1
TDs/INTs
12/7
11/78
Sacks/Yards
11/75
1390
Rush Yards
829
220
Attempts
213
6.32
YPC
3.89
21
TDs
8
Fumbles Lost
1
Interceptions
7
18/22 81.8%
Redzone
21/26 80.8%
30/67 0%
3rd Down
36/78 0%
0/4 0%
4th Down
6/11 0%
138
Total
136
61
Pass
61
67
Rush
56
10
Penalty
19
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Penalties/Yards
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Louisville vs. Syracuse Odds Comparison

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Louisville at Syracuse Team Totals

MatchupOverUnder
Louisville
3-3
N/A
N/A
Syracuse
2-3
N/A
N/A